Director, Externally Sponsored Research

Socket.dev; Redwood City (CA); On-site; USD 211,000 - 264,000; Full time

Benefits offered by this job

Hybrid work

Job summary

Revolution Medicines is seeking a Director, Externally Sponsored Research (ESR) to lead ESR strategy, oversight, and execution across a disease area. You will ensure scientific rigor, regulatory compliance, and alignment with company objectives, partnering with Medical Strategy, Clinical Operations, and other teams.

You will head ESR committees, supervise the ESR manager, and drive external collaborations with investigators, KOLs, and cooperative groups, while maintaining timely communication

Qualifications

• Advanced scientific or medical degree required (PhD, PharmD, MD).
• 10+ years of experience in Medical Affairs and ESRs within biotech/pharma.
• Proven ability to develop and execute medical research strategies.
• Experience in ESR program leadership including funding and study execution.
• Ability to navigate cross-functional partnerships with Legal, Compliance, Regulatory, and Clinical teams.
• Strong analytical and strategic thinking with the ability to assess proposals for merit and alignment.
• Excellent communication, interpersonal, and presentation skills for internal and external stakeholders.
• Deep knowledge of global regulatory requirements for Medical Affairs (FDA, EMA, ICH, GVP).

Responsibilities

• Oversee end-to-end ESR process for a disease area including proposal review, funding, and execution.
• Set scientific and strategic objectives and ensure ESR alignment.
• Represent ESR program within the organization and lead cross-functional committees.
• Maintain regulatory and legal compliance across ESR activities.
• Monitor ESR progress, milestones, and data dissemination.
• Optimize ESR program scalability and operational efficiency.
• Supervise the ESR manager assigned to the program.
• Serve as a primary contact for ESR-related interactions with internal and external stakeholders.
• Collaborate with Clinical Operations on budgeting, enrollment, and metrics.

Skills

Leadership

Strategic thinking

Communication

Cross-functional collaboration

Analytical thinking

Education

PhD/MD/PharmD

Job description

Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

The Opportunity:

The Director, Externally Sponsored Research (ESR) (including investigator sponsored trials and collaborative research) will lead the strategy, oversight, and execution of Revolution Medicines' ESR processes within one of our disease areas. This role will ensure scientific rigor, compliance, and alignment of the ESR program with company and external regulatory guidelines. The individual will collaborate closely with internal and external stakeholders to drive excellence in external research. Specifically, this individual will partner with Medical Strategy, Clinical Operations, and others on strategic development and execution of the program. The opportunity involves leadership of ESR-specific scientific committees and broad visibility within the organization. The Director, ESR, reports to the head of the ESR program.

Externally Sponsored Research Program Leadership

• Oversee the end-to-end ESR process for a specific disease area, including development of areas of interest, proposal review, approval, funding, and execution.
• Help set scientific and strategic objectives and ensure that ESRs align.
• Represent ESR program within the organization.
• Lead cross-functional scientific committees in proposal and protocol reviews.
• Maintain compliance with regulatory and legal requirements.
• Monitor ongoing ESRs progress, ensuring milestone tracking, study reporting, and data dissemination.
• Optimize ESR program scalability and operational efficiency, including systematic tracking of proposals, funding allocations, and study outcomes.
• Will directly supervise the ESR manager assigned to the program.

Cross-Functional & External Stakeholder Collaboration

• Serve as a key point of contact for ESR-related interactions with internal and external stakeholders.
• Partner with Clinical Operations on execution of the ESR program, including contracting, budgets, enrollment, and metrics.
• Work closely with Medical Affairs, Clinical Development, Preclinical, and other teams to align ESR funding with strategic priorities.
• Build relationships with external medical and scientific communities, including external investigators, KOLs, and cooperative groups.
• Ensure timely and transparent communication with investigators, maintaining strong external partnerships.

Required Skills, Experience and Education:

• Advanced scientific or medical degree (PhD, PharmD, MD).
• 10+ years of experience in Medical Affairs and ESRs within the biotechnology or pharmaceutical industry.
• Proven ability to develop and execute medical research strategies aligned with company and scientific priorities.
• Experience in ESR program leadership, including proposal review, funding allocation, and study execution.
• Ability to navigate cross-functional partnerships with Legal, Compliance, Regulatory, and Clinical teams.
• Strong analytical and strategic thinking skills with the ability to assess research proposals for scientific merit and alignment.
• Excellent communication, interpersonal, and presentation skills to engage internal and external stakeholders effectively.
• Deep knowledge of global regulatory requirements for Medical Affairs, including FDA, EMA, ICH, GVP, and industry best practices.

Preferred Skills:

• Prior experience in oncology, precision medicine, or targeted therapies.
• Familiarity with digital tools and platforms for grant submissions and ESR management.

  #LI-Hybrid #LI-YG1

The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.

Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.

Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.

Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact [e-mail].

Base Pay Salary Range

$211,000 — $264,000 USD