Director, Enterprise TPRM Operations & Governance

Vertex Pharmaceuticals LLC; Boston (MA); Hybrid; USD 176,000 - 264,000; Full time

Benefits offered by this job

Annual bonus

Equity awards

Health, dental, vision benefits

Paid time off including company shut

Job summary

Vertex Pharmaceuticals LLC in Boston, MA, seeks a Director of Enterprise Third-Party Risk Management Operations & Governance to drive end-to-end TPRM execution and scalability across the enterprise.

In this role you will partner with TPRM leadership, risk SMEs, sourcing teams and MSPs to ensure governance, risk assessment, remediation, monitoring and executive reporting, while advancing automation and process improvements.

Qualifications

• Strong analytical and project management skills.
• Exceptional leadership, communication, and stakeholder management skills.
• Familiarity with third-party risk assessment tools, dashboards, and governance frameworks.
• Ability to lead cross-functional teams and drive operational excellence.
• Track record of delivering measurable outcomes through process transformation, automation, and user experience redesign.

Responsibilities

• Lead operational integration of existing and newly established TPRM processes to create a seamless end-to-end third-party risk experience.
• Partner with TPRM leadership to translate strategic priorities into operational execution plans and measurable outcomes.
• Ensure consistent execution and oversight of supplier criticality, risk assessment, issue management, ongoing monitoring, and remediation processes.
• Identify and remove operational bottlenecks while driving improved efficiency and stakeholder experience.
• Support implementation and stabilization of expanded TPRM capabilities and operating models.
• Own development and execution of TPRM governance routines, including operational reviews, risk escalation forums, and executive reporting.
• Establish meaningful performance measurements and service-level metrics across the TPRM ecosystem.
• Develop clear and actionable reporting for senior leadership focused on program effectiveness, risk trends, capacity, and operational health.
• Ensure alignment between TPRM operational performance and enterprise risk management objectives.
• Provide leadership oversight of external TPRM service providers and operational partners.
• Establish performance standards, service expectations, escalation pathways, and continuous improvement mechanisms.
• Drive operational readiness planning to support increasing assessment volumes, geographic expansion, and future program maturity.
• Evaluate resource models, workflows, and capabilities required for long-term program scalability.
• Elevate partnerships across Strategic Sourcing, Legal, Compliance, Information Security, Quality, Finance, Enterprise Risk Management, and business functions.
• Act as a trusted advisor to stakeholders on TPRM operational processes, governance expectations, and risk escalation practices.
• Drive alignment among risk owners, business stakeholders, and operational teams to ensure consistent decision-making and accountability.
• Facilitate communication across functions to improve transparency, responsiveness, and overall program effectiveness.
• Identify opportunities to simplify, standardize, and optimize TPRM processes.
• Partner with process, technology, and analytics leaders to improve user experience and operational effectiveness.
• Support implementation of automation, reporting enhancements, and workflow improvements that increase productivity and scalability.
• Champion operational excellence principles and promote a culture of accountability, service, and continuous improvement.

Skills

Strategic leadership

Analytical skills

Project management

Stakeholder management

Cross-functional collaboration

Communication

Education

Bachelor’s degree in Business, Finance, Risk Management, or related field

Professional certifications (CRMA, CTPRP, CISM) preferred

Tools

Third-party risk assessment tools

Dashboards and governance frameworks

Job description

Vertex Pharmaceuticals LLC in Boston, MA, seeks a Director of Enterprise Third-Party Risk Management Operations & Governance to drive end-to-end TPRM execution and scalability across the enterprise.

In this role you will partner with TPRM leadership, risk SMEs, sourcing teams and MSPs to ensure governance, risk assessment, remediation, monitoring and executive reporting, while advancing automation and process improvements.