Director, End to End Systems Integration (Hybrid)
Merck & Co.
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Job summary
Merck & Co. is seeking a Director of End-to-End Systems Integration within Global Clinical Supplies. The role oversees SAP integrations (IRT, RTSM, Veeva, vendor interfaces) and ensures robust, monitored, scalable connectivity across the clinical supply ecosystem.
You will partner with IT, SMEs, and business system owners to align priorities. You will drive KPI tracking, risk mitigation, and continuous improvement, while ensuring GxP compliance and validation expectations are met.
Qualifications
- Bachelor's degree required in a related field.
- 10+ years in pharma, biotech, supply chain, IT, or related industry.
- 5+ years supporting complex system integrations involving SAP.
Responsibilities
- Own strategy and operational framework for end-to-end systems integrations.
- Monitor health of critical integrations and define KPIs.
- Coordinate triage and resolution of integration defects with IT and vendors.
- Drive dashboards, reporting, and management reviews.
- Collaborate across GCS teams, IT, SMEs, and vendors.
Skills
Education
Tools
Job description
As part of the Global Clinical Supplies (GCS) organization, the Director, End-to-End Systems Integration will be responsible for the strategy, operational robustness, and continuous improvement of all GCS-facing systems integrations, with a primary focus on SAP integrations, including (but not limited to) IRT, Veeva, and external vendor interfaces. This role will ensure that integration services are stable, monitored, and aligned to business needs across the clinical supply ecosystem.
Reporting to the Senior Director, Head of Clinical Supply Systems, this position will partner closely with business system owners, IT, subject matter experts (SMEs), and external vendors to ensure integration performance, reliability, and issue resolution are managed proactively. The role will also oversee the health monitoring framework for integrations, including definition and tracking of KPIs, incident trends, root cause analysis, and remediation activities.
- Own the strategy and operational framework for GCS-facing end-to-end systems integrations.
- Partner with business system owners, IT, and SMEs to align integration priorities with business process needs, system roadmaps, and operational risk.
- Support governance discussions related to integration dependencies, enhancements, upgrades, and lifecycle management.
- Ensure integration approaches are consistent with enterprise architecture, data flow standards, and validation expectations.
- Oversee processes for monitoring the health of critical integrations, including proactive detection of issues, exception handling, and escalation management.
- Work closely with IT support teams to define, track, and report integration KPIs and recurring incident trends.
- Coordinate triage and resolution of integration defects or failures in collaboration with IT, vendors, and business system owners.
- Drive visibility into integration performance through dashboards, status reporting, and management reviews.
- Serve as the key connector between GCS business teams, IT, and Business System Owners for integration-related strategy and execution.
- Facilitate timely decision-making across stakeholder groups by translating technical issues into business impact and business needs into technical requirements.
- Partner with SMEs to define functional requirements, data mapping needs, exception handling, and operational support processes.
- Support vendor coordination for interface changes, upgrades, testing, and production support.
- Support the strategy for continuous improvement of integration robustness, reliability, and scalability.
- Identify and prioritize opportunities to reduce manual intervention, improve automation, strengthen controls, and simplify integration architecture.
- Lead or support root cause analysis and corrective/preventive actions for recurring integration issues.
- Contribute to long-term planning for future-state integration capabilities and resilience.
- Ensure integration changes are assessed for business impact, tested appropriately, and implemented with adequate controls and documentation.
- Support release planning, cutover readiness, and hypercare for integration-related deployments.
- Collaborate with IT and business teams to ensure effective operational support models are in place for ongoing integration services.
- Ensure compliance with relevant GxP, validation, and data integrity requirements where applicable.
- Bachelor's degree in Supply Chain, Computer Science, Information Technology, Engineering, Life Sciences, or a related field.
- Minimum of 10 years of progressive experience in pharmaceutical, biotechnology, supply chain, IT, or related industry.
- Minimum of 5 years of experience supporting complex system integrations, interface operations, or digital technology initiatives involving SAP.
- Demonstrated experience working with SAP integrations, IRT/RTSM, Veeva, and external vendor interfaces in a regulated business environment.
- Strong understanding of SAP Supply Chain Management functionality
- Strong understanding of integration platforms, including OpenText, Informatica, and SAP BTP
- Experience defining and tracking KPIs and service metrics for digital system health and performance.
- Familiarity with validation, change control, SDLC, and GxP expectations in regulated environments.
- Proven ability to influence and coordinate across business system owners, IT, SMEs, and vendors without direct line authority.
- Strong stakeholder management, communication, and issue resolution skills.
- Ability to translate between business needs and technical implementation considerations.
- Advanced degree such as a Master's or MBA.
- Experience with dashboarding, service reporting, or integration observability tools.
- Prior exposure to clinical supply chain, clinical operations, or pharmaceutical manufacturing systems.
- Certifications in project management, IT service management, or systems integration are a plus.
Clinical Supply Chain Management, Clinical Trial Management, Cross-Functional Leadership, Data Analysis, Decision Making, IT Process Improvement, Project Strategy, Regulatory Compliance, Results-Oriented, Risk Management, SAP Development, SAP Management, Strategic Planning, Strategic Thinking, System Integration
Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.
As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit: EEOC Know Your Rights EEOC GINA Supplement
We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another's thinking and approach problems collectively.
Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.
We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance
We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles' Fair Chance Initiative for Hiring Ordinance
The salary range for this role is $173,200.00 - $272,600.00
This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee's position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.
The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.
We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits .
Travel Requirements: 10%
Flexible Work Arrangements: Hybrid
Shift: 1st - Day
Valid Driving License: No
Hazardous Material(s): n/a
Job Posting End Date: 09/7/2026
Requisition ID: R412572
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