Director, Early Safety Immunology

Boehringer Ingelheim; Ridgefield (CT); On-site; USD 200,000 - 316,000; Full time

Job summary

Boehringer Ingelheim is seeking a Director Early Safety Immunology to lead immune safety across discovery, preclinical and clinical development, developing models and technologies to support portfolio decisions.

The role emphasizes mentoring staff, collaboration across Nonclinical/Early Safety Sciences, CPS TAs, CI and Discovery Research, and adherence to regulatory expectations to inform senior leadership decisions.

Qualifications

• Ph.D. in Immunology or equivalent with roughly ten (10) years’ experience in the pharmaceutical industry.
• Extensive experience in laboratory-based immune safety assessments and mechanistic derisking studies, and ability to lead scientists.
• Strong management and supervisory skills with proven experience in leading and developing staff, including senior scientists.
• Excellent written and verbal communications skills; ability to operate in dynamic, evolving environments.

Responsibilities

• Manages a team conducting investigative toxicology studies (focus immune safety) across discovery, preclinical and clinical development.
• Provides scientific oversight of Early Safety Immunology, including strategy, context, evaluating output/reports, and delivering results to senior management.
• Maintains operational control of functions within Early Safety Immunology, including balancing assignments, workload, standards/compliance, and resource distribution.
• Guides interpretation of computational, molecular, in vitro, cellular and immunotoxicology data for mechanisms of immune safety liabilities and development of biomarkers/tools.
• Maintains up-to-date expertise and identifies opportunities/trends to develop new avenues of work.
• Ensures fit-for-purpose and modality-driven early safety strategies for immune concepts.
• Provides bottom lines and recommendations to senior management (Global Head, VP & above).
• Collaborates with IU and other teams to drive early identification and mitigation of safety risks.
• Complies with ICH, FDA, EPA, OSHA and company regulations.

Skills

Immune safety assessments

Mechanistic derisking

Staff leadership

Communication skills

Publications in immunology/toxicology

Written/verbal communication

Education

Ph.D. in Immunology or equivalent

Job description

As an employee of Boehringer Ingelheim, you will actively contribute to the discovery, development, and delivery of our products to our patients and customers. Our global presence provides an opportunity for all employees to collaborate internationally, offering visibility and the opportunity to directly contribute to the company's success. We realize that our strength and competitive advantage lie with our people. We support our employees in several ways to foster a healthy working environment, meaningful work, mobility, networking, and work-life balance. Our competitive compensation and benefit programs reflect Boehringer Ingelheim's high regard for our employees. The primary objective of the Director Early Safety Immunology role is to lead Early Safety immunology, tasked with proactively developing and utilizing novel models/technologies to ensure tailored, modality driven safety evaluations of immune therapeutics during discovery, preclinical and clinical development. The incumbent ensures appropriate assignment of scientists to projects, suitable technology and collaborative investments, and delivery of the highest quality mechanistic data/interpretation to support portfolio decisions. Guiding the professional and personal development of staff is a critical responsibility for this role. The position works closely with the other functional heads within Nonclinical/Early Safety Sciences, CPS TAs, CI and Discovery Research to drive early identification, understanding and mitigation of immune-related safety risks.

Description

As an employee of Boehringer Ingelheim, you will actively contribute to the discovery, development, and delivery of our products to our patients and customers. Our global presence provides an opportunity for all employees to collaborate internationally, offering visibility and the opportunity to directly contribute to the company's success. We realize that our strength and competitive advantage lie with our people. We support our employees in several ways to foster a healthy working environment, meaningful work, mobility, networking, and work-life balance. Our competitive compensation and benefit programs reflect Boehringer Ingelheim's high regard for our employees. The primary objective of the Director Early Safety Immunology role is to lead Early Safety immunology, tasked with proactively developing and utilizing novel models/technologies to ensure tailored, modality driven safety evaluations of immune therapeutics during discovery, preclinical and clinical development. The incumbent ensures appropriate assignment of scientists to projects, suitable technology and collaborative investments, and delivery of the highest quality mechanistic data/interpretation to support portfolio decisions. Guiding the professional and personal development of staff is a critical responsibility for this role. The position works closely with the other functional heads within Nonclinical/Early Safety Sciences, CPS TAs, CI and Discovery Research to drive early identification, understanding and mitigation of immune-related safety risks.

Duties & Responsibilities

• Manages a team conducting investigative toxicology studies (focus immune safety) supporting early discovery, preclinical and clinical development; implementing nontraditional approaches to advance/rescue compounds and to predict and/or understand immune mediated toxicities
• Provides scientific oversight of Early Safety Immunology, including developing strategy, establishing context (internal & external), evaluating output/reports, and ensuring accurate delivery of results to senior management and project teams
• Maintains operational control of functions within Early Safety Immunology, including balancing assignments, monitoring workload, maintaining standards/compliance and distributing resources
• Guides interpretation of computational, molecular, in vitro, cellular and immunotoxicology data and supports the utilization of these data for understanding mechanisms of immune safety liabilities, in developing novel biomarkers, and/or in developing predictive & analytical tools
• Maintains up-to-date expertise in pertinent scientific and regulatory areas and identifies opportunities/trends to develop and guide new avenues of work
• Ensures fit for purpose and modality driven early safety strategies for innovative immune modulating concepts
• Provides bottom lines and recommendations to senior management (Global Head, VP & above)
• Complies with all ICH, FDA, EPA, OSHA and company regulations and policies
• Excellent collaboration with a wide range of scientists within the IU and maintaining a network of resources both internally and externally to develop projects/strategies appropriately to achieve critical goals

Requirements

• Ph.D. in Immunology or equivalent with roughly ten (10) years’ experience in the pharmaceutical industry required
• Extensive experience in laboratory-based immune safety assessments, mechanistic derisking studies, and the ability to lead the scientists engaged in these studies
• Well-developed management and supervisory skills, with proven experience in leading and developing staff, including senior scientists
• Ability to operate effectively in dynamic, evolving environments and guide teams through ambiguity
• Established reputation and/or publication record, preferably in the fields of immunology, toxicology, or cell/molecular biology
• Excellent written and verbal communications skills
• Onsite/Flex*: This position is site based with flexibility for remote working. Working onsite a minimum of 2-3 days per week is required. Remote working norms will be clarified during the interview process

Eligibility Requirements

• Must be legally authorized to work in the United States without restriction
• Must be willing to take a drug test and post-offer physical (if required)
• Must be 18 years of age or older

Compensation Data

The base salary range for this position is $200,000.00 to $316,000.00 USD. The position may be eligible for a role specific discretionary bonus, relocation, and/or other compensation elements. We continuously review market data and may adjust salary ranges as needed in the future. Actual compensation will be based on job-related factors such as skills, experience, and qualifications, and other factors permitted by law. For an overview of our benefits please click here.

Our Company

Boehringer Ingelheim is a biopharmaceutical company active in both human and animal health. As one of the industry's top investors in research and development, the company focuses on developing innovative therapies that can improve and extend lives in areas of high unmet medical need. Independent since its foundation in 1885, Boehringer takes a long-term perspective, embedding sustainability along the entire value chain. Our approximately 54,300 employees serve over 130 markets to build a healthier and more sustainable tomorrow. Learn more at www.boehringer-ingelheim.com.

Why Boehringer Ingelheim?

With us, you can develop your own path in a company with a culture that knows our differences are our strengths - and break new ground in the drive to make millions of lives better.

Here, your development is our priority. Supporting you to build a career as part of a workplace that is independent, authentic and bold, while tackling challenging work in a respectful and friendly environment where everyone is valued and welcomed.

Alongside, you have access to programs and groups that ensure your health and wellbeing are looked after - as we make major investments to drive global accessibility to healthcare. By being part of a team that is constantly innovating, you'll be helping to transform lives for generations.

Want to learn more? Visit https://www.boehringer-ingelheim.com