Director, Commercial Supply Chain

Vertex Pharmaceuticals; Boston (MA); Hybrid; USD 182,000 - 273,000; Full time

Job summary

Vertex is seeking a Director of Supply Chain Management for Cell and Gene Therapy to lead the global commercial supply chain planning, strategy and operations for the Type 1 Diabetes program. The role coordinates long-term capacity builds across the CDMO network, conducts supply risk assessments, and ensures end-to-end supply chain readiness for commercialization.

The Director will establish internal compliance and business processes, build the processes, systems and people for launch readiness,

Qualifications

• Bachelor's degree in a scientific or business discipline.
• Typically requires 10 years of experience or the equivalent combination of education and experience.
• Demonstrated ability to plan and optimize resources (budgets, staff, technology).
• Knowledge of cGMP, GCP, GDP, import/export and Part 11; ERP/MRP systems.
• Strong analytical and problem-solving skills with complex judgement.
• Experience building and leading high-performing teams.
• Experience coordinating global supply chain networks across CDMO and internal teams.

Responsibilities

• Lead overall supply chain strategy and operations for the Type 1 Diabetes program.
• Implement Global S&OP process.
• Lead long-term capacity build across CDMO network.
• Define and deliver on supply chain program goals.
• End-to-end process mapping and delivery to patients.
• Implement governance for commercial supply chain including CDMO and internal manufacturing.

Skills

Strategic planning

Supply chain leadership

Analytical thinking

Stakeholder management

Team building

Education

Bachelor's degree in a scientific or business discipline

Tools

ERP/MRP systems (Oracle OPM)

Job description

General Summary

The Director, Supply Chain Management, Cell and Gene Therapy will lead the global commercial supply chain planning, strategy and operations for Vertex’s Type 1 Diabetes (T1D) program. The strategy includes long term capacity build plans across the CDMO network, supply risk assessments, slot management and accountability for end-to-end supply chain operations throughout the patient journey. The Director is responsible for establishing internal compliance and business processes in support of commercialization. The Director is accountable for building the processes, systems and people to ensure Supply Chain launch readiness.

Job Description

General Summary

The Director, Supply Chain Management, Cell and Gene Therapy will lead the global commercial supply chain planning, strategy and operations for Vertex’s Type 1 Diabetes (T1D) program. The strategy includes long term capacity build plans across the CDMO network, supply risk assessments, slot management and accountability for end-to-end supply chain operations throughout the patient journey. The Director is responsible for establishing internal compliance and business processes in support of commercialization. The Director is accountable for building the processes, systems and people to ensure Supply Chain launch readiness.

The Supply Chain Director has proven experience both managing and influencing large scale global supply chain networks. A leader in building both internal and external collaborations, the Director has advanced business acumen. The Director will have responsibility for the management and operations of a large group within the Supply Chain team. The Director has proven supervisory and leadership capabilities. As the leader of key supplier working teams, the Director will optimize interdisciplinary understanding and synergy within the groups and integrate activities with both the cross-functional team as well as manufacturers.

Key Duties And Responsibilities

• Lead overall supply chain strategy and operations for successful commercialization of Type 1 Diabetes program
• Implement Global S&OP process
• Lead recommendation for long term capacity build including multi-year investments across CDMO network
• Define and deliver on supply chain program goals
• End to end process mapping, ownership and delivery to patient
• Implement governance for commercial supply chain operations including CDMO and internal manufacturing
• Deliver Commercialization SOPs for inspection readiness and GxP compliance
• Aligns Supply Chain model with Commercial patient management model
• Identify and implement new processes and capabilities needed to support Cell and Gene Therapy programs including a forum for collaboration with Vertex’s Cell and Gene Therapy site
• Anticipate future industry trends and keep abreast with a strong foundational of knowledge of manufacturing and supply
• Work in matrix team to ensure overall program readiness including Clinical, Systems, Logistics and International
• Represent Supply Chain across several governance forums as well as Network Strategy

Knowledge And Skills

• Demonstrated ability to successfully plan and optimize all resources of an area (budgets, staff, technology, etc.) for advancement of all goals and objectives
• Ability to apply complex judgement and advanced analytical thought to develop novel/innovative solutions
• Strong overall business acumen and understanding of the industry and business drivers
• Highly specialized depth of knowledge on regulations relating to pharmaceutical supply chain activities (cGMP, GCP, GDP, import/export, computer systems/Part 11) as well as ERP/MRP systems, Oracle OPM
• Exceptional analytical and problem solving skills, often addressing novel/unusual situations and exercising complex judgement based on significant technical experience and interpretive thinking
• Exceptional skills in preparing and presenting informational and compelling reports, delivering to a variety of audiences
• Drives effective, productive business relationships across the function and the organization
• Highly skilled in managing customer, stakeholder or leadership expectations, communicating in complex or sensitive situations, facilitating mutually beneficial outcomes and influencing/guiding others to adopt a new point of view; skilled negotiator, able to resolve complex problems
• Strong experience in building and managing high-performing teams

Education And Experience

• Bachelor's degree in a scientific or business discipline
• Typically requires 10 years of experience or the equivalent combination of education and experience

At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision‑making, drive innovation, increase efficiency, and help deliver better outcomes for patients.

Pay Range

$181,800 - $272,600

Disclosure Statement

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job‑related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market‑leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week‑long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation

Hybrid-Eligible Or On-Site Eligible

Flex Eligibility Status

In this Hybrid-Eligible role, you can choose to be designated as:

• Hybrid: work remotely up to two days per week; or select
• On‑Site: work five days per week on‑site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non‑discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E‑Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at [e-mail]