Director, Business Development at Jade Biosciences

Matcha; Northern (KY); Hybrid; USD 250,000 - 275,000; Full time

Job summary

Jade Biosciences is seeking a Director of Business Development to lead licensing, partnerships, and deal execution across the full spectrum of BD activities. The role reports to the CFO and requires strong cross-functional engagement with R&D, clinical, regulatory, and legal teams.

The candidate will develop financial models, present recommendations to senior management, and build strategic relationships with biotech peers, pharma companies, and academic partners while driving governance and

Qualifications

• Bachelor's degree or higher with 8+ years in biotech or life sciences business development.
• Deep understanding of scientific, clinical, and regulatory dynamics driving value in therapeutics.
• Proven track record in negotiating and closing complex transactions in biotech.

Responsibilities

• Lead and drive BD activities including in-licensing, out-licensing, co-development, and partnerships.
• Coordinate cross-functional diligence with R&D, regulatory, IP, legal, and finance.
• Develop business cases, valuation frameworks, and transaction rationale for senior leadership.
• Structure and finalize term sheets, LOIs, NDAs, and definitive agreements with legal and exec teams.
• Support presentations for senior management and the Board of Directors.
• Build relationships with biotech peers, pharma companies, and academic institutions.
• Serve as a primary contact for partners, ensuring professional oversight and strategic insight.
• Support alliance transition and governance post-signing for successful execution.
• Collaborate with internal leaders across research, development, manufacturing, and commercial.
• Synthesize scientific, clinical, strategic, and financial factors to drive internal alignment.
• Contribute to portfolio prioritization and long-range planning.
• Develop financial frameworks to analyze potential transactions.

Skills

Business development

Licensing

Deal structuring

Negotiation

Cross-functional collaboration

Financial modeling

Strategic planning

Education

Bachelor's degree

MBA/MD/PhD preferred

Job description

About Jade Biosciences

Jade Biosciences is a clinical-stage biotechnology company focused on developing best-in-class therapies that address critical unmet needs in autoimmune diseases. Jade’s lead candidate, JADE101, targets the cytokine APRIL, and is currently being evaluated in a Phase 1 clinical trial for the treatment of immunoglobulin A nephropathy. Jade’s pipeline also includes JADE201, an afucosylated anti-BAFF-R monoclonal antibody, as well as JADE301, an undisclosed antibody candidate, both currently in preclinical development.Jade was launched based on assets licensed from Paragon Therapeutics, an antibody discovery engine founded by Fairmount. For more information, visitJadeBiosciences.comand follow the Company onLinkedIn.

Role Overview

We are looking for a Director, Business Development who will move fluidly across the full spectrum of business development activity including opportunity evaluation, diligence, deal structuring, transaction execution, and partnership governance and who brings the same level of rigor to a valuation model as they do to a board presentation. This position reports to the CFO.

Key Responsibilities

• Lead or play a central role in all business development activities, including evaluation and execution of in-licensing opportunities, out-licensing, co-development and co-commercialization agreements, research collaborations and platform partnerships, option-based deals, key supply agreements, geographic licensing arrangements, and joint ventures or other structured transactions.
• Coordinate cross-functional diligence processes involving R&D, technical operations/CMC, clinical, regulatory, legal, IP, finance, commercial, and executive leadership.
• Develop business cases, valuation frameworks, competitive assessments, and transaction rationale to support internal decision-making.
• Structure, negotiate, and finalize term sheets, letters of intent, confidentiality agreements, and definitive agreements in collaboration with legal and executive leadership.
• Support preparation of presentations and recommendations for senior management, executive committees, and the Board of Directors.
• Build and maintain strong relationships with biotechnology peers, pharmaceutical companies and academic institutions.
• Serve as a key point of contact for existing and prospective partners, representing the company with professionalism, credibility, and strategic insight.
• Support alliance transition and post-signing governance as needed to help ensure successful execution of strategic collaborations.
• Partner closely with internal leaders across research, development, manufacturing, commercial, finance, legal, intellectual property, investor relations, and corporate strategy.
• Help drive internal alignment on external opportunities by synthesizing complex scientific, clinical, strategic, operational, and financial considerations.
• Contribute to broader corporate planning efforts, including portfolio prioritization discussions, long range planning and strategic reviews.
• Develop financial frameworks to properly analyze potential transactions.

Qualifications

• Bachelor’s degree and 8+ years of experience in business development within biotech or life sciences, with a strong focus on technology licensing, research collaborations, and strategic transactions; MBA, MD or PhD preferred
• Deep understanding of the scientific, clinical, and regulatory dynamics that drive value in therapeutic development, with the ability to engage credibly with R&D and development teams
• Proven track record of successfully negotiating and closing complex transactions, demonstrating strong strategic judgment and financial and transactional acumen
• Highly effective at synthesizing large amounts of scientific, clinical, and financial information into clear, compelling recommendations for senior leadership
• Demonstrated ability to operate with executive-level visibility and discretion, managing confidential processes across internal and external stakeholders
• Strong cross-functional instincts and the ability to build alignment across diverse teams without losing momentum

Position Location

This is a remote role; periodic travel to team and company events is required.

The anticipated salary range for candidates for this role is $250 - $275k. The final salary offered will depend on several factors, which may include, but not limited to, relevant years of experience, educational background, and geography.

As part of the I-9 verification of authorization to work in the United States, Jade Bioscience participates in E-Verify. To learn more about E-Verify please review thisposter.

Jade Biosciences is proud to be an Equal Opportunity employer. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected Veteran status, age, or any other characteristic protected by law.