Director, Applied AI Architect

Immunic Inc.; United States; Remote; USD 140,000 - 220,000; Full time

Job summary

Immunic Inc. is seeking an Applied AI Architect to shape the company's AI foundation across R&D, Commercial, and G&A. You will define the enterprise AI architecture and drive the roadmap for agentic systems while partnering with teams across the business.

The role combines strategic thinking with hands-on execution, with a focus on scalable, compliant AI solutions and cost-aware operations for a growing enterprise.

Qualifications

• 8+ years of enterprise architecture or AI engineering experience.
• Experience building agentic AI solutions in regulated environments.
• Strong knowledge of cloud infrastructure and enterprise data platforms.

Responsibilities

• Define and maintain Immunic’s AI architecture and design patterns across business groups and functions.
• Lead discovery with business teams to identify, qualify, and prioritize use cases tied to outcomes.
• Bridge business needs and technical execution across Research, Development, Medical, Commercial, and G&A.
• Provide technical leadership to AI engineers and cross-functional stakeholders.
• Monitor technology spend (FinOps) and optimize AI-related compute and token usage as adoption scales.

Skills

Enterprise architecture

AI engineering

Strategic thinking

Communication & influence

Education

Bachelor’s degree in CS/Engineering

Master’s degree preferred

Tools

Cloud platforms

AI frameworks

Job description

Summary

We are seeking an Applied AI Architect to shape the company's technology landscape across R&D, Commercial, and G&A functions. Reporting to the Chief Data & Digital Officer, you will act as both a strategic thinker and hands‑on builder, defining Immunic’s technology architecture and AI foundation, driving the roadmap for agentic systems, and partnering closely with teams across the enterprise.

You will join us at an important point before Phase 3 data readout and help shape the technology foundation for the enterprise. The ideal candidate combines a product mindset with hands‑on execution.

Responsibilities

• Define and maintain Immunic’s AI architecture, establishing scalable standards and design patterns across business groups and functions.
• Lead discovery with business teams to identify, qualify, and prioritize use cases tied to outcomes.
• Understand modern AI systems, frontier LLM models, agentic applications, model evaluation, retrieval, or enterprise AI workflows.
• Partner with Research, Development, Medical, Commercial, and G&A functions to bridge business needs and technical execution, guide platform selection, integration, and buy-versus-build decisions.
• Establish practical guardrails and repeatable patterns that enable teams to move quickly and safely.
• Provide technical leadership and mentorship to AI engineers and cross‑functional stakeholders.
• Monitor technology spend (FinOps) and optimize AI‑related compute and token usage as adoption scales, adapting architectural approaches to an evolving AI cost landscape.

Qualifications & Education

• Bachelor’s degree in Computer Science, Engineering, or a related technical field or equivalent experience. Master’s degree preferred.
• 8+ years of enterprise architecture, AI engineering, or a related technical discipline, including proficiency with AI coding agents and workflows.
• Demonstrated experience building agentic AI solutions in a regulated environment.
• Strong knowledge of [technical area, regulations, systems or tools].
• Strong knowledge of cloud infrastructure and networking, enterprise data platforms, and system architecture, with the ability to collaborate effectively with business stakeholder teams.
• Excellent communication and influencing skills; ability to operate strategically while being hands‑on.
• Willingness and ability to travel approximately 25–40% of the time, including internationally.
• Experience in evaluating emerging AI technologies, frameworks, and platforms preferred.

Immunic Therapeutics is an Equal Opportunity Employer. We are committed to fostering a diverse, inclusive, and equitable workplace where all individuals are valued and respected. Employment decisions are based on qualifications, merit, and business needs, without regard to race, color, religion, gender, sexual orientation, national origin, disability, veteran status, or any other protected status.

Please note, Immunic does not accept unsolicited resumes from external agencies or recruiters. Submission of a resume without a prior written agreement does not create any express or implied contract between Immunic and the agency. Immunic will not pay any fees related to unsolicited resumes.