Director, Antibody Discovery

Incyte; Wilmington (DE); On-site; USD 190,000 - 230,000; Full time

Job summary

Incyte Corporation, a biopharmaceutical company focused on oncology and inflammation, seeks a Director of Antibody Discovery to lead strategy and execution of antibody discovery campaigns. The role directs project teams, collaborates with immunologists and pharmacologists, and manages external CROs and internal resources to advance therapeutic antibodies and antibody fragments.

The position requires an advanced degree and extensive experience in antibody technologies and platform development,

Qualifications

• Ph.D. in biochemistry, molecular biology, cell biology, or related field.
• Extensive knowledge of antibody discovery using hybridoma, single cell B cloning and display technologies.
• Experience with immunization approaches to enhance immune responses against challenging antigens.
• Experience leading a diverse scientific team and managing a research group.

Responsibilities

• Lead antibody discovery using immunization and/or display technologies.
• Direct external collaborations for discovery and optimization of biotherapeutic compounds.
• Support establishment and management of new technology platforms for antibody discovery.
• Collaborate with immunologists and pharmacologists to drive target validation and discovery programs.
• Utilize CROs and internal resources to optimize discovery processes across diverse teams.
• Manage a team of scientists supporting antibody discovery and technology development.
• Establish and manage ambitious timelines for multiple discovery projects.
• Participate as an in-house specialist in due diligences.
• Responsible for NGS platform implementation for antibody discovery.

Skills

Leadership

Collaboration

Project management

Due Diligences

Education

Ph.D. in biochemistry, molecular biology, cell biology, or related field

Tools

NGS platforms

Job description

Overview Incyte is a biopharmaceutical company focused on the discovery, development, and commercialization of novel medicines to meet serious unmet medical needs in oncology and inflammation and autoimmunity. Incyte is committed to the rigorous pursuit of research and development excellence to improve the lives of patients, make a difference in health care, and build sustainable value.

Overview Incyte is a biopharmaceutical company focused on the discovery, development, and commercialization of novel medicines to meet serious unmet medical needs in oncology and inflammation and autoimmunity. Incyte is committed to the rigorous pursuit of research and development excellence to improve the lives of patients, make a difference in health care, and build sustainable value. The Company strives to discover and develop first-in-class and best-in-class medicines-advancing a diverse portfolio of large and small molecules.

Job Summary (Primary Function) The Director, Antibody Discovery implements, develops, and operates the antibody discovery platforms. The position directs the discovery of therapeutic and tool antibody campaigns, operate as project or technology leader on Biotherapeutic Research campaigns, and participate as a key resource on managing and supporting external collaborations.

Essential Functions Of The Job (Key Responsibilities)

• Lead antibody discovery using immunization and/or display technologies.
• Direct external collaborations for the discovery and optimization of biotherapeutic compounds
• Support the establishment and management of new technology platforms for antibody discovery.
• Collaborate with immunologists and pharmacologists to drive target validation and discovery programs.
• Utilize Contract Research Organizations (CROs) and internal resources for optimizing discovery processes, ensuring inclusivity and collaboration across diverse teams.
• Manage a team of scientists supporting Ab discovery and technology development.
• Establish and manage ambitious timelines for multiple discovery projects.
• Participate as an in-house specialist in Due Diligences.
• Responsible for NGS platform implementation for Ab. Discovery.

Qualifications (Minimal acceptable level of education, work experience, and competency)

• Advanced degree (Ph.D.) in biochemistry, molecular biology, cell biology, or related field, plus relevant experience in antibody discovery.
• Extensive knowledge and hands-on experience in antibody discovery using hybridoma, single cell B cloning and/or display technologies for the discovery of antibodies and antibody fragments.
• Experience with immunization approaches for enhancing immune responses to challenging antigens is desired.
• Experience in antibody optimization/characterization is preferred.
• Extensive knowledge of molecular biology and bioinformatics.
• Demonstrate ability to work in a highly collaborative team environment.
• Experience leading a diverse scientific team.
• Experience managing a scientific group

Disclaimer: The above statements are intended to describe the general nature and level of work performed by employees assigned to this job. They are not intended to be an exhaustive list of all duties, responsibilities, and qualifications. Management reserves the right to change or modify such duties as required.

Incyte Corporation is committed to creating a diverse environment and is proud to be an equal opportunity employer.

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