Cyber Defense Analyst Massachusets onsite

IPolarity LLC; Whippany (NJ); Hybrid; USD 120,000 - 180,000; Full time

Benefits offered by this job

Flexible work from home

Job summary

Alnylam seeks a Senior Cyber Defense Analyst to oversee the SentinelOne EDR platform, optimizing its deployment across endpoints and coordinating security operations. You will monitor endpoints, detect threats, respond to incidents, and triage vendor support cases to ensure timely remediation.

You will also monitor Microsoft 365, Azure, AWS, and directory services, perform threat hunting with SIEM/EDR tools, and support cybersecurity requirements across Clinical, Manufacturing, Quality, and

Qualifications

• Senior Cyber Defense Analyst with experience in EDR, SIEM, threat detection and response.
• Experience supporting GxP-regulated environments and validated systems.
• Strong collaboration with Infrastructure, Cloud, Manufacturing, Quality Assurance, Compliance and Application teams.

Responsibilities

• Oversee SentinelOne EDR operations, including deployment, monitoring, and tuning.
• Lead threat detection, incident response, and remediation coordination across teams.
• Triage security alerts, investigate incidents, and document findings.
• Coordinate vendor support and ensure timely mitigations.
• Support cybersecurity requirements for regulated environments (GxP) and validated systems.

Skills

Azure Sentinel

Threat Intelligence Services

EDR

Framework design

SentinelOne

Endpoint Protection

Job description

Role: Cyber Defense Analyst Location: Hybrid - Cambridge, MA (3 days onsite/2 days remote)

Top Skills Required : 1.Azure Sentinel, 2.Cyber Threat Intell. Services, 3.EDR, Framework design, 4.SentinelOne 5.Endpoint Protec.

Job Description/ Responsibilities : Strong Senior Cyber Defense Analyst in the administration, optimization, and operational management of the SentinelOne EDR platform. Responsibilities include endpoint security monitoring, threat detection and response, troubleshooting security incidents, coordinating vendor support cases, and supporting cybersecurity requirements across Research, Clinical, Manufacturing, Quality, and Corporate functions. The resource will also assist in monitoring and responding to ZeroFox alerts, performing alert triage, validation, investigation, risk assessment, documentation, and escalation activities to ensure timely mitigation of potential cybersecurity threats.

Additional Alnylam-Relevant Responsibilities:

• Support cybersecurity operations for GxP-regulated systems supporting Clinical, Quality, Manufacturing, and Laboratory environments.
• Monitor and investigate security events across Microsoft 365, Azure, AWS, Active Directory, Entra ID, and cloud-based applications.
• Perform threat hunting activities using EDR, SIEM, threat intelligence, and cloud security tools.
• Review and respond to security incidents affecting laboratory systems, manufacturing systems, research environments, and business applications.
• Support cybersecurity requirements for validated systems, electronic records, and regulated data environments.
• Collaborate with Infrastructure, Cloud, Manufacturing, Quality Assurance, Compliance, and Application teams to remediate security risks.
• Analyze phishing attempts, business email compromise (BEC), malware, ransomware, insider threats, and suspicious user activities.
• Assist with vulnerability management activities, including risk assessment, remediation tracking, and security exception reviews.
• Develop and maintain Incident Response Playbooks, SOPs, Disaster Recovery, and Cybersecurity Runbooks.
• Support cybersecurity audits, vendor risk assessments, and compliance reviews.

Flexible work from home options available.