Cryo-EM Specialist: Advanced Electron Microscopy

SLAC National Accelerator Laboratory; Menlo Park (CA); On-site; USD 90,000 - 130,000; Full time

Job summary

SLAC National Accelerator Laboratory in Menlo Park seeks a Cryo-EM Specialist to support state-of-the-art electron microscopy facilities, including seven Thermo Fisher cryoEM instruments and two cryoET systems with preparation tooling. The team handles oversight, operations, maintenance, and user training across single particle and tomography studies.

The successful candidate will conduct specimen preparation, operate microscopes, screen samples, and assist researchers, contributing to

Qualifications

• Bachelor's degree in relevant field and at least two years of relevant work experience.
• Knowledge ofscientific principles and understanding of TEM/cryoEM concepts.
• Excellent analytical and problem-solving abilities.

Responsibilities

• Conduct cryoEM specimen preparation.
• Operate electron microscopes for cryo-specimen study.
• Screen cryo-EM specimens for suitability in structural research.
• Perform preliminary image data quality evaluation and tune microscopes.
• Collect image data for users and evaluate data quality.
• Interface with computing teams to ensure data collection, storage and processing.
• Perform image processing of cryoEM data.
• Assist researchers on cryoEM projects and supervise their experiments.
• Help orient and train new staff and users.
• Develop data collection enhancements and instructional materials.
• Maintain microscopes and preparation apparatus; log microscope performance.

Education

Bachelor's degree in structural biology, biophysics, physics, biochemistry, chemistry or bioengineering

Master’s degree in related field

Job description

SLAC National Accelerator Laboratory in Menlo Park seeks a Cryo-EM Specialist to support state-of-the-art electron microscopy facilities, including seven Thermo Fisher cryoEM instruments and two cryoET systems with preparation tooling. The team handles oversight, operations, maintenance, and user training across single particle and tomography studies.

The successful candidate will conduct specimen preparation, operate microscopes, screen samples, and assist researchers, contributing to