Core Immunology Laboratory (CIL) - Associate Specialist

University of California - San Francisco; San Francisco (CA); Sur place; USD 78 000 - 91 000; Plein temps

Résumé du poste

UCSF Health, AG is seeking a scientifically motivated researcher to process clinical biospecimens and drive quality for translational studies in San Francisco. You will design and optimize flow cytometry panels, perform biomarker assays, and support genomics workflows, with an emphasis on GCLP compliance.

The role requires Master’s-level training, hands-on experience with spectral flow cytometry, and strong organizational skills to manage multiple projects and training of staff.

Qualifications

• Master's degree in biology, biochemistry, immunology, medical laboratory science, or at least five to ten years of relevant experience.
• Hands-on laboratory research experience, including biological or clinical specimen processing.
• Experience with multicolor and/or spectral flow cytometry.
• Experience with sample preparation, QC, and laboratory documentation.
• Ability to work independently and flexibly, troubleshoot technical problems, manage multiple priorities, and meet project timelines.
• Strong organizational, communication, and teamwork skills.

Responsabilités

• Process, aliquot, store, and track clinical research specimens following study protocols, GCLP principles, and institutional requirements.
• Perform, optimize, and troubleshoot multiparameter and spectral flow cytometry; develop panels, controls, QC procedures, compensation/spectral unmixing, and data analysis.
• Perform and optimize ELISA, MSD, Luminex, and Olink assays; evaluate performance and collaborate on biomarker strategies.
• Support 10x Genomics single-cell workflows, including cell preparation, viability, counting, and QC; perform cell culture as needed.
• Contribute to experimental design, SOPs, assay protocols, QC documentation, data analysis, and scientific reports; provide training.

Connaissances

Multicolor flow cytometry

Laboratory documentation

Independent problem solving

Teamwork and communication

Troubleshooting technical issues

Formation

Master's degree in biology/related field

Outils

FlowJo

SpectroFlo

LDMS/ELR

Specimen-tracking systems

Description du poste

Position description

• [Clinical Biospecimen Processing & Quality] Process, aliquot, store, and track clinical research specimens following study protocols, GCLP principles, and institutional requirements. Troubleshoot processing issues and contribute to audit readiness and continuous quality improvement.
• [Flow Cytometry & Core Operations] Perform, optimize, and troubleshoot multiparameter and spectral flow cytometry. Develop multicolor panels, controls, and QC procedures; perform compensation/spectral unmixing and data analysis. Support instrument readiness, assay scheduling, reagent management, and user training.
• [Immunoassays & Biomarker Analysis] Perform and optimize ELISA, MSD, Luminex, and Olink assays. Evaluate assay performance, QC, and technical variability and collaborate with investigators on biomarker strategies.
• [Genomics & Translational Research] Support 10x Genomics single-cell workflows, including cell preparation, viability, counting, and QC. Perform cell culture and cellular assays as needed.
• [Scientific & Laboratory Support] Contribute to experimental design, SOPs, assay protocols, QC documentation, data analysis, and scientific reports. Provide technical guidance and training to laboratory personnel. Support compliance with GCLP, and study-specific requirements.

Required qualifications

• Master's degree in biology, biochemistry, immunology, medical laboratory science, or at least five to ten years of experience in the relevant field.
• Hands-on laboratory research experience, including biological or clinical specimen processing.
• Experience with multicolor and/or spectral flow cytometry.
• Experience with sample preparation, QC, and laboratory documentation.
• Ability to work independently and flexibly, troubleshoot technical problems, manage multiple priorities, and meet project timelines.
• Strong organizational, communication, and teamwork skills.

Preferred qualifications

• Advanced experience with spectral/multiparameter flow cytometry, panel design, QC, and data analysis.
• Experience with clinical research biospecimens in GCLP/GLP or quality-focused environments.
• Experience in HIV, infectious disease, vaccine, cancer, immunology, or other translational research.
• Experience with ELISA, MSD, Luminex, Olink, 10x Genomics, cell culture, or cellular assays.
• Experience developing assays, maintaining SOPs/QC documentation, and training or mentoring laboratory personnel.
• Familiarity with FlowJo, SpectroFlo, LDMS/electronic laboratory records, or specimen-tracking systems.

Salary

See Table 24B for the salary range for this position. A reasonable estimate for this position is $78,300-$91,100.

Application Requirements

• Curriculum Vitae - CV must clearly list current and/or pending qualifications (e.g. board eligibility/certification, medical licensure, etc.).
• Cover Letter
• Statement of Research (Optional)
• Statement of Teaching (Optional)

Reference requirements

• 2-4 required (contact information only)

About UC San Francisco

As a University employee, you will be required to comply with all applicable University policies and/or collective bargaining agreements, as may be amended from time to time. Federal, state, or local government directives may impose additional requirements.

The University of California is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, protected veteran status, or other protected status under state or federal law.

UCSF is committed to welcoming and serving all people, honoring the dignity of every individual without preference or prejudice, in support of its public mission and in alignment with our PRIDE values and Principles of Community.

As a condition of employment, the finalist will be required to disclose if they are subject to any final administrative or judicial decisions within the last seven years determining that they committed any misconduct.

• "Misconduct" means any violation of the policies or laws governing conduct at the applicant's previous place of employment, including, but not limited to, violations of policies or laws prohibiting sexual harassment, sexual assault, or other forms of harassment, or discrimination, as defined by the employer.
• UC Sexual Violence and Sexual Harassment Policy
• UC Anti-Discrimination Policy
• APM - 035: Affectionate Action and Nondiscrimination in Employment

Job location

San Francisco, CA