Core Immunology Laboratory (CIL) - Associate Specialist

UC San Francisco Academic; San Francisco (CA); Sur place; USD 78 000 - 91 000; Plein temps

Résumé du poste

UCSF Department of Physical Therapy and Rehabilitation Science in San Francisco seeks an Associate Specialist to support the Core Immunology Laboratory. You will process clinical biospecimens, perform multicolor and spectral flow cytometry, and assist with immunoassays and biomarker analyses.

The role emphasizes quality control, GCLP compliance, data analysis, and training of lab personnel. Requires a Master’s degree and 5–10 years of relevant experience; salary range is $78,300–$91,100 annually.

Qualifications

• Master’s degree in biology, biochemistry, immunology, medical laboratory science required.
• Hands-on laboratory research experience in biospecimen processing and immunology.
• Experience with multicolor and/or spectral flow cytometry.
• Ability to work independently, troubleshoot, manage priorities, and meet timelines.
• Strong organizational and teamwork skills.

Responsabilités

• Process, aliquot, store, and track clinical research specimens per protocols and GCLP.
• Perform multiparameter flow cytometry and data analysis; develop panels and QC procedures.
• Perform ELISA, MSD, Luminex, and Olink assays and evaluate performance.
• Support 10x Genomics single-cell workflows and cell culture as needed.
• Contribute to experimental design, SOPs, QC documentation, and training of staff.

Connaissances

Multicolor flow cytometry

Spectral flow cytometry

GCLP compliance

Data analysis

Cell culture

Assay development

Troubleshooting

Formation

Master’s degree in biology, biochemistry, immunology, medical laboratory science

Outils

FlowJo

SpectroFlo

LDMS

Specimen-tracking systems

Description du poste

The Core Immunology Laboratory (CIL) is now recruiting for an Associate Specialist. Position duties include:
[Clinical Biospecimen Processing & Quality] Process, aliquot, store, and track clinical research specimens following study protocols, GCLP principles, and institutional requirements. Troubleshoot processing issues and contribute to audit readiness and continuous quality improvement.
[Flow Cytometry & Core Operations] Perform, optimize, and troubleshoot multiparameter and spectral flow cytometry. Develop multicolor panels, controls, and QC procedures; perform compensation/spectral unmixing and data analysis. Support instrument readiness, assay scheduling, reagent management, and user training.
[Immunoassays & Biomarker Analysis] Perform and optimize ELISA, MSD, Luminex, and Olink assays. Evaluate assay performance, QC, and technical variability and collaborate with investigators on biomarker strategies.
[Genomics & Translational Research] Support 10x Genomics single-cell workflows, including cell preparation, viability, counting, and QC. Perform cell culture and cellular assays as needed.
[Scientific & Laboratory Support] Contribute to experimental design, SOPs, assay protocols, QC documentation, data analysis, and scientific reports. Provide technical guidance and training to laboratory personnel. Support compliance with GCLP, and study-specific requirements.

Required qualifications:
Master’s degree in biology, biochemistry, immunology, medical laboratory science, or at least five to ten years of experience in the relevant field.
Hands-on laboratory research experience, including biological or clinical specimen processing.
Experience with multicolor and/or spectral flow cytometry.
Experience with sample preparation, QC, and laboratory documentation.
Ability to work independently and flexibly, troubleshoot technical problems, manage multiple priorities, and meet project timelines.
Strong organizational, communication, and teamwork skills.

Preferred qualifications:
Advanced experience with spectral/multiparameter flow cytometry, panel design, QC, and data analysis.
Experience with clinical research biospecimens in GCLP/GLP or quality-focused environments.
Experience in HIV, infectious disease, vaccine, cancer, immunology, or other translational research.
Experience with ELISA, MSD, Luminex, Olink, 10x Genomics, cell culture, or cellular assays.
Experience developing assays, maintaining SOPs/QC documentation, and training or mentoring laboratory personnel.
Familiarity with FlowJo, SpectroFlo, LDMS/electronic laboratory records, or specimen-tracking systems.

See Table 24B for the salary range for this position. A reasonable estimate for this position is $78,300-$91,100.

• Master’s degree in biology, biochemistry, immunology, medical laboratory science, or at least five to ten years of experience in the relevant field.