Computational Biologist I, Simmons Cancer Center

UT Southwestern Medical Center; Dallas (TX); On-site; USD 80,000 - 110,000; Full time

Benefits offered by this job

Healthcare benefits

PTO and paid holidays

On-site childcare

Job summary

UT Southwestern Medical Center in Dallas, TX is seeking a Computational Biologist I to support the Choi Lab in processing large-scale multi-omics data and developing computational methods for protein design. You will collaborate with the PI and a multidisciplinary team to analyze genomic, single-cell, spatial, and clinical datasets, translate findings, and contribute to machine learning efforts.

The role focuses on building and maintaining workflows, software tools, and databases, documenting

Qualifications

• Master's degree in CS or related field of biological science, or bachelor's in CS/biological science
• At least 2 years of related research experience in bioinformatics and computational biology

Responsibilities

• Manage research laboratory computer hardware and software programming and maintenance.
• Perform complex data analysis related to specialized research methodologies and results as assigned by the PI.
• Develop and/or modify software to support new and ongoing research projects.
• Resolve hardware, software, and network issues in support of the lab.
• Develop and maintain complex databases to support new and ongoing research projects.
• Train laboratory staff in the use of pertinent research systems.
• May specialize in bioinformatics, software development, network administration, or hardware/software maintenance.
• Perform other duties as assigned.

Skills

Bioinformatics

Computational biology

Data analysis

Software development

Education

Master's degree in CS or related field of biological science

Bachelor's degree in CS or related field of biological science

Job description

WHY UT SOUTHWESTERN?

With over 75 years of excellence in Dallas-Fort Worth, Texas, UT Southwestern is committed to excellence, innovation, teamwork, and compassion. As a world-renowned medical and research center, we strive to provide the best possible care, resources, and benefits for our valued employees. Ranked as the number 1 hospital in Dallas-Fort Worth according to U.S. News & World Report, we invest in you with opportunities for career growth and development to align with your future goals. Our highly competitive benefits package offers healthcare, PTO and paid holidays, on-site childcare, wage, merit increases and so much more. We invite you to be a part of the UT Southwestern team where you'll discover a culture of teamwork, professionalism, and a rewarding career!

WHY UT SOUTHWESTERN?

With over 75 years of excellence in Dallas-Fort Worth, Texas, UT Southwestern is committed to excellence, innovation, teamwork, and compassion. As a world-renowned medical and research center, we strive to provide the best possible care, resources, and benefits for our valued employees. Ranked as the number 1 hospital in Dallas-Fort Worth according to U.S. News & World Report, we invest in you with opportunities for career growth and development to align with your future goals. Our highly competitive benefits package offers healthcare, PTO and paid holidays, on-site childcare, wage, merit increases and so much more. We invite you to be a part of the UT Southwestern team where you'll discover a culture of teamwork, professionalism, and a rewarding career!

Job Summary

Perform professional work in support of scientific research using technical knowledge of software, software development, networking, and/or hardware in a complex computing environment. Subject matter expert in multiple areas of computing technology, and specific knowledge of molecular biology and genetics. Works collaboratively with Principal Investigator ("PI") to determine the most suitable computational methods and tools to analyze large-scale biological data sets. Prepare reports for presentation or publication. Responsible for assisting PI in meeting the system needs for multiple research projects and/or labs. The Choi Laboratory within the Center for Cellular Therapies and Cancer Immunology at UT Southwestern conducts interdisciplinary research at the intersection of cancer immunology, cellular therapy, immune engineering, and AI-enabled biomedical discovery. The Computational Biologist I will work collaboratively with the Principal Investigator, Dr. Jaehyuk Choi, and a multidisciplinary team of computational and experimental researchers 1) to analyze and manage large-scale genomic, single-cell, spatial, clinical, and other multi-omic datasets and 2) to implement novel computational methods to analyze and engineer new proteins. The position will help identify, implement, and refine appropriate bioinformatics, statistical, and computational methods to produce reproducible analyses and translate complex data into meaningful biological insights. Responsibilities include developing and maintaining computational workflows, software tools, databases, and research computing resources; supporting data visualization and interpretation; and contributing to machine-learning and other advanced analytical approaches as appropriate to project needs. The Computational Biologist I will document code, methods, and results; prepare analyses and reports for presentations, publications, and collaborative discussions; and provide technical support and training related to laboratory computational systems. This position will support multiple collaborative research projects aimed at advancing the understanding of immune biology and accelerating the development of innovative cellular and immune-based therapies.

Benefits

UT Southwestern is proud to offer a competitive and comprehensive benefits package to eligible employees. Our benefits are designed to support your overall wellbeing, and include:

• PPO medical plan, available day one at no cost for full-time employee-only coverage
• 100% coverage for preventive healthcare-no copay
• Paid Time Off, available day one
• Retirement Programs through the Teacher Retirement System of Texas (TRS)
• Paid Parental Leave Benefit
• Wellness programs
• Tuition Reimbursement
• Public Service Loan Forgiveness (PSLF) Qualified Employer
• Learn more about these and other UTSW employee benefits!

Required

• Education Master's Degree In Computer Science or a related field of biological science or Bachelor's Degree In Computer Science or a related field of biological science
• Experience 2 years Related research experience in bioinformatics and computational biology with Bachelor's Degree

Job Duties

• Manage research laboratory computer hardware and software programming and maintenance. Ensure existing systems meet the continuing needs of the lab and/or recommend and test new systems as necessary.
• Perform complex data analysis related to specialized research methodologies and results as assigned by the PI.
• Develop and/or modify software to support new and ongoing research projects.
• Resolve hardware, software, and network issues in support of the lab.
• Develop and maintain complex databases to support new and ongoing research projects.
• Train laboratory staff in the use of pertinent research systems.
• May specialize in bioinformatics, software development, network administration, or hardware/software maintenance.
• Perform other duties as assigned.

SECURITY AND EEO STATEMENT

Security

This position is security-sensitive and subject to Texas Education Code 51.215, which authorizes UT Southwestern to obtain criminal history record information.

EEO

UT Southwestern Medical Center is committed to an educational and working environment that provides equal opportunity to all members of the University community. As an equal opportunity employer, UT Southwestern prohibits unlawful discrimination, including discrimination on the basis of race, color, religion, national origin, sex, sexual orientation, gender identity, gender expression, age, disability, genetic information, citizenship status, or veteran status.

Primary Location

Texas-Dallas-5323 Harry Hines Blvd

Work Locations

5323 Harry Hines Blvd

Job

Research & Laboratory

Organization

371021 - SCC-Jae Choi Lab

Schedule

Full-time

Shift

Day Job

Employee Status

Regular

Job Type

Standard

Job Posting

Aug 14, 2026, 2:38:58 AM