Compound Operations Manager – Discovery Chemistry (Hybrid Onsite)

The Fountain Group; Cambridge (MA); Hybrid; USD 55,000 - 78,000; Full time

Job summary

The Fountain Group is seeking a Compound Manager in Cambridge, MA for a 6-month assignment with 2-3 days onsite. You will oversee registration, storage, distribution, and inventory control of discovery compounds, ensuring accurate metadata and data integrity across databases.

You will collaborate with Medicinal Chemistry, Biology, DMPK, and CROs to support programs, while developing SOPs and coordinating domestic and international shipments according to regulations.

Qualifications

• 3+ years of compound management or related pharmaceutical research operations.
• Hands-on registration and electronic compound database management.
• Chemical structure and nomenclature knowledge.
• Compound handling, storage, inventory control, and laboratory safety practices.
• Compound metadata and data integrity management.

Responsibilities

• Manage registration, receipt, storage, distribution, inventory control, and quality oversight of chemical compounds supporting discovery research.
• Register newly synthesized and externally sourced compounds in electronic compound databases using established nomenclature and registration standards.
• Maintain compound metadata including chemical structure, molecular weight, purity, salt form, inventory location, and sample history.
• Reconcile physical compound inventories against electronic records and investigate discrepancies.
• Coordinate domestic and international compound shipments and transfers in accordance with applicable regulations and company policies.
• Develop and maintain SOPs, work instructions, and training materials for compound management workflows.
• Investigate deviations related to inventory, labeling, shipping, and database records and implement corrective actions.
• Support CRO and vendor operations involving compound synthesis, purification, analytical testing, storage, and logistics.
• Partner with Medicinal Chemistry, Biology, DMPK, Analytical Sciences, Informatics, and external CROs to support discovery programs.

Skills

Compound management

Medicinal chemistry support

Pharmaceutical operations

SOP development

Excel

Database management

Inventory reconciliation

Logistics coordination

CRO/vendor management

Electronic lab systems

Education

Bachelor's degree in Chemistry

MS in Chemistry preferred

Tools

BIOVIA

Dotmatics

CDD Vault

ChemAxon

Job description

The Fountain Group is seeking a Compound Manager in Cambridge, MA for a 6-month assignment with 2-3 days onsite. You will oversee registration, storage, distribution, and inventory control of discovery compounds, ensuring accurate metadata and data integrity across databases.

You will collaborate with Medicinal Chemistry, Biology, DMPK, and CROs to support programs, while developing SOPs and coordinating domestic and international shipments according to regulations.