Clinical Trial Manager

Green Life Science; San Francisco (CA); On-site; USD 130,000 - 160,000; Full time

Job summary

An innovative biotech firm is seeking a Clinical Trial Manager to lead early-phase oncology trials. This role offers the chance to work on groundbreaking therapies that can change the lives of cancer patients. You will manage complex studies, ensuring compliance with regulatory standards while collaborating with cross-functional teams. The position promises a dynamic work environment where your contributions will significantly impact clinical outcomes. Join a passionate team dedicated to advancing transformative oncology therapies and enjoy a competitive compensation package along with equity participation.

Benefits

Competitive compensation

Equity participation

Comprehensive benefits package

Collaborative culture

Qualifications

• 5+ years of clinical trial management experience, especially in oncology.
• Strong knowledge of ICH-GCP and FDA regulations.

Responsibilities

• Manage all aspects of assigned clinical trials ensuring timelines and quality standards.
• Coordinate cross-functional teams to support trial execution.
• Monitor clinical trial progress and implement risk mitigation strategies.

Skills

Clinical Trial Management

Oncology Expertise

Regulatory Compliance

Project Management

Vendor Management

Communication Skills

Problem-Solving

Education

Bachelor's degree in life sciences

Advanced degree (preferred)

Job description

Job Title: Clinical Trial Manager – Oncology

Location: San Francisco Preferred

Reports to: Director Clinical Operations

Position Type: Full-time

Salary Range: $130,000 - $160,000

Company Overview:

Our Biotech are an innovative, early-stage biotechnology company dedicated to advancing transformative oncology therapies. With two assets currently in Phase I and Phase II clinical development, we are building a dynamic team committed to rigorous science, clinical excellence, and improving outcomes for cancer patients.

Position Summary:

We are seeking a highly motivated and experienced Clinical Trial Manager (CTM) to lead the execution of our early-phase oncology clinical trials. The ideal candidate will have hands-on experience in managing complex oncology studies from start-up through completion and thrive in a fast-paced, cross-functional biotech environment. This role will be instrumental in driving clinical trial strategy and execution in alignment with regulatory and operational standards.

Key Responsibilities:

• Manage all aspects of assigned clinical trials (Phase I–II) including planning, execution, and oversight, ensuring timelines, budgets, and quality standards are met.
• Serve as the primary point of contact for CROs, vendors, and clinical sites; oversee their performance and ensure adherence to protocols and GCP.
• Develop and maintain study documentation (protocols, investigator brochures, ICFs, CRFs, monitoring plans, etc.).
• Lead site start-up activities including feasibility assessments, site selection, and contract/budget negotiation.
• Coordinate cross-functional teams (clinical operations, data management, regulatory, medical, and pharmacovigilance) to support trial execution.
• Monitor clinical trial progress, proactively identify risks, and implement mitigation strategies.
• Participate in the review of clinical data and contribute to clinical study reports and regulatory submissions.
• Ensure compliance with all regulatory and ethical requirements including ICH GCP and FDA regulations.
• Provide input on clinical development plans and contribute to long-term strategy as the company advances assets through development stages.

Qualifications:

• Bachelor's degree in life sciences or related field (advanced degree preferred).
• 5+ years of clinical trial management experience, including at least 3 years in oncology and early-phase trials.
• Prior experience in a small biotech or startup environment preferred.
• Strong knowledge of ICH-GCP, FDA regulations, and clinical trial processes.
• Demonstrated ability to manage CROs and third-party vendors effectively.
• Proven ability to work independently in a fast-paced, lean team setting.
• Excellent organizational, communication, and problem-solving skills.
• Willingness to travel as needed (up to 25%).

Why Join Us?

• Opportunity to work on cutting-edge oncology programs with high potential.
• Collaborative, entrepreneurial culture where your contributions make a real impact.
• Competitive compensation, equity participation, and comprehensive benefits package.