Senior Clinical Trial Manager

Barrington James; United States; Remote; USD 100,000 - 135,000; Full time

Job summary

Join a forward-thinking biotech company as a Senior Clinical Trial Manager, leading global oncology trials that transform patient care. This role offers the chance to manage complex studies, ensuring compliance with regulatory standards while collaborating with cross-functional teams. With a commitment to innovation and excellence, this dynamic team is dedicated to advancing cancer therapeutics. If you're passionate about making a difference in the oncology field and thrive in a fast-paced environment, this opportunity is perfect for you.

Qualifications

• 6-8 years of clinical trial management experience with oncology focus.
• Strong knowledge of GCP, ICH guidelines, and FDA regulations.

Responsibilities

• Lead planning and execution of oncology clinical trials.
• Manage vendors and clinical sites to meet timelines and budgets.

Skills

Clinical Trial Management

Oncology Expertise

Regulatory Compliance

Vendor Management

Communication Skills

Problem-Solving Skills

Education

Bachelor's Degree in Life Sciences

Advanced Degree (Preferred)

Tools

Clinical Trial Management Systems (CTMS)

eTMF

Microsoft Office Suite

Job description

Direct message the job poster from Barrington James

Job Title: Senior Clinical Trial Manager (Oncology)

Location: Remote/Flexible with 50–70% travel

Department: Clinical Operations

Reports To: VP, Clinical Operations

About Us:

My client is a fast-growing, innovative oncology biotech company dedicated to transforming the treatment landscape for patients with unmet medical needs. Their mission is to advance cutting-edge cancer therapeutics through high-quality clinical development and strategic partnerships. Join a dynamic team at the forefront of science and patient care.

Position Summary:

The Senior Clinical Trial Manager (Sr. CTM) will lead and manage global and/or regional oncology clinical trials, ensuring high-quality execution, regulatory compliance, and timely delivery. This role involves strategic oversight of vendors and clinical sites, with frequent travel (50%–70%) to support site management, monitoring, and team collaboration.

Key Responsibilities:

• Lead the planning, execution, and delivery of complex oncology clinical trials in accordance with ICH-GCP, SOPs, and regulatory requirements.
• Manage and oversee vendors, and clinical sites to ensure study timelines, budgets, and quality objectives are met.
• Serve as the primary point of contact for operational aspects of assigned studies, including protocol development, feasibility, site selection, and patient recruitment strategies.
• Conduct or support on-site visits including site initiation, monitoring, and close-out visits as needed.
• Collaborate with cross-functional teams (clinical science, regulatory, data management, biostatistics, and medical affairs) to drive study progress.
• Ensure effective issue identification, resolution, and escalation across study activities.
• Develop and maintain clinical study documents including protocols, ICFs, monitoring plans, and clinical study reports (CSRs).
• Support regulatory submissions, audits, and inspections.

Qualifications:

• Bachelor’s degree in life sciences or related field (advanced degree preferred).
• Minimum 6–8 years of clinical trial management experience, including 3+ years in oncology (early and/or late phase).
• Demonstrated experience leading global trials and working with CROs and external vendors.
• Strong knowledge of GCP, ICH guidelines, FDA regulations, and clinical trial best practices.
• Ability to manage multiple priorities in a fast-paced, dynamic environment.
• Excellent communication, leadership, and organizational skills.
• Willingness and ability to travel 50–70% of the time (domestic and international).
• Proficiency in clinical trial management systems (CTMS), eTMF, and Microsoft Office Suite.

Preferred Attributes:

• Experience in immuno-oncology, rare tumors, or precision medicine approaches.
• Start-up or small biotech experience.
• Strong problem-solving skills and the ability to think critically under pressure.

To apply, please send your resume to [e-mail]

Seniority level

• Seniority level

  Mid-Senior level

Employment type

• Employment type

  Full-time

Job function

• Job function

  Science and Research

• Industries

  Biotechnology Research and Pharmaceutical Manufacturing

Referrals increase your chances of interviewing at Barrington James by 2x

Get notified about new Clinical Trial Manager jobs in United States.

Assistant Clinical Study Manager (Remote)

Remote: Clinical Trial Disclosure & Transparency Manager

Clinical Trial Disclosure & Transparency Manager

United States $100,000.00-$135,000.00 2 days ago

United States $140,000.00-$150,000.00 1 week ago

Clinical Trial Disclosure and Transparency Manager

Clinical Research Manager - Shockwave Medical (Remote)

United States $85,000.00-$100,000.00 7 hours ago

Clinical Project Manager – East Coast, USA | Remote

Boston, MA $80,000.00-$95,000.00 2 weeks ago

United States $150,000.00-$170,000.00 5 hours ago

Thousand Oaks, CA $40.00-$45.00 1 week ago

We’re unlocking community knowledge in a new way. Experts add insights directly into each article, started with the help of AI.