Clinical Research Program Lead — Immunology & Genomics

Broad Institute; Cambridge (MA); On-site; USD 120,000 - 180,000; Full time

Benefits offered by this job

Medical insurance

Dental insurance

Vision insurance

Life insurance

Disability insurance

401(k) plan

Paid holidays

Paid time off

Parental leave

Job summary

The Broad Institute invites applications for a Clinical Research Program Manager to lead clinical research operations within a multidisciplinary GaMBiT initiative, partnering with Massachusetts General Hospital. You will supervise study staff, ensure protocol adherence, and coordinate data integration across clinical and molecular analyses.

Working across Broad Institute and MGH, you will design human subjects research protocols, manage budgets, and drive recruitment strategies while maintaining

Qualifications

• Bachelor’s degree in a related field; 7+ years clinical or human subjects research experience.
• Master’s degree in public health, biology, or clinical research; 5+ years leadership in academic settings.
• Minimum 2 years of experience training and supervising a team of clinical research staff.
• Excellent strategic planning and project/program management skills for multi‑study leadership.
• Data management expertise with complex clinical research databases and data extraction.
• Strong written and verbal communication abilities.

Responsibilities

• Manage day-to-day operations of multiple clinical research studies in inflammatory and immune-mediated conditions.
• Collaborate with principal investigators and multidisciplinary teams to design and implement human subjects research protocols.
• Supervise, train, and support Clinical Research Coordinators and study staff, including patient recruitment and biospecimen handling.
• Coordinate study initiation, regulatory compliance, and safety monitoring plans.
• Prepare and submit IRB materials, amendments, and continuing reviews.
• Liaise among investigators, staff, IRB, sponsors, core labs, and collaborating teams.
• Develop study operations manuals, SOPs, CRFs, and other documentation.
• Establish project plans, milestones, risks, and ensure alignment with goals.
• Report progress at meetings and generate study-related reports for stakeholders.
• Oversee databases and workflows to maintain data quality and integrity.
• Coordinate collection and transfer of biospecimens for multi-omics analyses.
• Facilitate data and biospecimen sharing with collaborators per data use agreements.

Skills

Organizational skills

Analytical problem-solving

Cross-functional collaboration

Interpersonal skills

Education

Bachelor's degree in related field

Master's degree in public health, biology, or clinical research

Tools

REDCap

Job description

The Broad Institute invites applications for a Clinical Research Program Manager to lead clinical research operations within a multidisciplinary GaMBiT initiative, partnering with Massachusetts General Hospital. You will supervise study staff, ensure protocol adherence, and coordinate data integration across clinical and molecular analyses.

Working across Broad Institute and MGH, you will design human subjects research protocols, manage budgets, and drive recruitment strategies while maintaining