CLINICAL PROJECT MANAGER II – IMMUNOLOGY (Sponsor Dedicated/ Remote- US)

1001 Syneos Health, LLC; North Carolina; Hybrid; USD 110,000 - 150,000; Full time

Job summary

Syneos Health is seeking a Clinical Project Manager II – Immunology for a sponsor-dedicated, fully remote US role. The candidate will lead global immunology trials, coordinating with cross-functional teams and vendors to ensure timely, compliant execution across multiple indications and phases, with up to 25% travel.

The role requires 3+ years of hands-on CPM experience in immunology, strong trial operations knowledge, and proven ability to manage studies across diverse regions while maintaining

Qualifications

• 3+ years of Clinical Project Management experience supporting global immunology trials.
• Experience managing studies across multiple countries and regions.
• Vendor management experience is required.
• Strong understanding of clinical trial operations and lifecycle.
• Experience across Phase I–IV immunology studies.
• Familiar with ICH-GCP guidelines and regulations.
• Proficiency with Microsoft Office Suite.
• Ability to work within global, cross-functional matrix organizations.

Responsibilities

• Drive operational execution and delivery of global immunology trials.
• Partner with study leads and cross-functional teams on global trials.
• Lead day-to-day study management across startup, conduct, maintenance, and closeout.
• Manage timelines, deliverables, risks, and issue resolution.
• Oversee external vendors and CROs.
• Coordinate team meetings and action-item follow-up.
• Support study-level planning, forecasting, and strategy execution.
• Monitor study performance metrics and intervene as needed.
• Ensure inspection readiness and regulatory compliance.
• Collaborate with stakeholders across functions and report study status.

Skills

CPM experience

Global trials

Vendor management

ICH-GCP knowledge

Microsoft Office

Cross-functional teamwork

Education

Bachelor's degree in a scientific/healthcare field

Tools

Microsoft Office Suite

Job description

CLINICAL PROJECT MANAGER II – IMMUNOLOGY (Sponsor Dedicated/ Remote- US)

Syneos Health® is a leading fully integrated biopharmaceutical solutions organization built to accelerate customer success. We translate unique clinical, medical affairs and commercial insights into outcomes to address modern market realities. Our Clinical Development model brings the customer and the patient to the center of everything that we do. We are continuously looking for ways to simplify and streamline our work to not only make Syneos Health easier to work with, but to make us easier to work for. Whether you join us in a Functional Service Provider partnership or a Full-Service environment, you’ll collaborate with passionate problem solvers, innovating as a team to help our customers achieve their goals. We are agile and driven to accelerate the delivery of therapies, because we are passionate to change lives. Discover what our 29,000 employees, across 110 countries already know: WORK HERE MATTERS EVERYWHERE

Why Syneos Health

We are passionate about developing our people, through career development and progression; supportive and engaged line management; technical and therapeutic area training; peer recognition and total rewards program. We are committed to our Total Self culture – where you can authentically be yourself. Our Total Self culture is what unites us globally, and we are dedicated to taking care of our people. We are continuously building the company we all want to work for and our customers want to work with. Why? Because when we bring together diversity of thoughts, backgrounds, cultures, and perspectives – we’re able to create a place where everyone feels like they belong.

Job Responsibilities

CLINICAL PROJECT MANAGER II – IMMUNOLOGY Sponsor Dedicated | Remote – United States. Are you passionate about advancing innovative therapies for patients living with autoimmune and inflammatory diseases? We are seeking experienced Clinical Project Managers with strong global immunology clinical trial experience to join a high-performing sponsor-dedicated team supporting a diverse portfolio of immunology studies across multiple indications and phases of development. This is a fully remote, US-based opportunity, with up to 25% travel, where you will play a critical role in the operational leadership and execution of global clinical trials. We are specifically seeking professionals with 3+ years of hands‑on Clinical Project Management experience leading global immunology studies and collaborating with cross‑functional teams, vendors, and international stakeholders.

WHAT YOU'LL DO

As a Clinical Project Manager II, you will help drive the operational execution and delivery of global immunology clinical trials, ensuring studies are conducted efficiently, compliantly, and according to established timelines.

• Support and partner with Clinical Study Leads and cross‑functional study teams on global immunology trials
• Lead day‑to‑day study management activities across study startup, conduct, maintenance, and closeout
• Manage study timelines, deliverables, risks, and issue resolution
• Oversee external vendors, CROs, central laboratories, specialty providers, and other study partners
• Coordinate Clinical Team meetings and drive action item follow‑up
• Support study‑level planning, forecasting, and operational strategy execution
• Monitor study performance metrics and proactively identify areas requiring intervention
• Ensure inspection readiness and compliance with applicable regulations and sponsor requirements
• Collaborate with stakeholders across Clinical Operations, Data Management, Biostatistics, Medical Monitoring, Regulatory Affairs, Safety, Supply Chain, and Quality
• Contribute to study status reporting and executive‑level communications
• Support achievement of study milestones, enrollment targets, database locks, and study closeout activities
• Travel up to 25%

WHAT YOU WILL BRING

Required Qualifications

• Bachelor's degree in a scientific, healthcare, or related field
• 3+ years of Clinical Project Management experience supporting global immunology clinical trials
• Experience managing studies across multiple countries and regions (North America, Europe, Asia‑Pacific, Latin America, or other global regions)
• Vendor management experience required
• Strong understanding of clinical trial operations and study lifecycle management
• Experience supporting Phase I, Phase II, Phase III, and/or Phase IV immunology studies
• Strong working knowledge of ICH‑GCP guidelines and clinical research regulations
• Proficiency with Microsoft Office Suite
• Ability to work effectively within global, cross‑functional matrix organizations

IMMUNOLOGY THERAPEUTIC AREA EXPERIENCE

Candidates should have direct clinical trial experience supporting one or more immunology indications, including but not limited to:

• Gastroenterology / Inflammatory Bowel Disease (IBD)
• Ulcerative Colitis (UC)
• Crohn's Disease (CD)
• Autoimmune and Inflammatory Diseases
• Rheumatoid Arthritis (RA)
• Psoriatic Arthritis (PsA)
• Ankylosing Spondylitis (AS)
• Axial Spondyloarthritis (axSpA)
• Systemic Lupus Erythematosus (SLE)
• Sjögren's Syndrome
• Vasculitis
• Other Autoimmune Disorders
• Dermatology
• Plaque Psoriasis
• Atopic Dermatitis (Eczema)
• Hidradenitis Suppurativa
• Vitiligo
• Other Immune‑Medicated Dermatologic Diseases
• Respiratory and Allergy
• Severe Asthma
• Eosinophilic Disorders
• Chronic Rhinosinus