Clinical Project Manager

Buck Institute; Novato (CA); On-site; USD 90,000 - 100,000; Full time

Benefits offered by this job

Health insurance

Paid parental leave

PTO

401k match

Job summary

The Buck Institute in Marin County, California, seeks an experienced Clinical Project Manager to lead day-to-day execution of two complex clinical studies, TIME and BETA, ensuring protocol compliance, data integrity, and timely delivery.

You will supervise staff, coordinate with stakeholders, manage budgets, regulatory filings, and quality of biospecimens, gaining visibility in a growing federally funded program within a dynamic nonprofit research environment.

Qualifications

• Experience managing concurrent studies and priorities.
• Problem solving, initiative, and follow-through.
• Supervisory/leadership experience.
• Strong written and verbal communication.
• Ability to meet deadlines and budget guidelines.
• Experience preparing or submitting IRB protocols, amendments, or continuing reviews.
• Clinical skills to oversee staff performing clinical procedures.

Responsibilities

• Lead day-to-day execution of clinical trials ensuring compliance with study protocols, GCP, ICH Guidelines and SOPs.
• Manage study collaborators and vendors to meet study needs and timelines.
• Monitor enrollment, milestones, and team capacity; flag risks to leadership.
• Coordinate protocol amendments, study close-out activities, and follow-up on deliverables.
• Maintain IRB compliance and regulatory documentation.
• Oversee data entry, queries, and good documentation practices across systems.
• Oversee safety reporting and escalation for adverse events and deviations.
• Train and mentor Clinical Research Associates; ensure appropriate staffing and coverage.
• Coordinate scheduling of participants, staff, and resources; adapt plans as priorities shift.
• Promote culturally competent, multilingual recruitment.

Skills

Organization

Problem-solving

Leadership

Communication

Budget discipline

IRB experience

Clinical mentoring

Education

High school diploma/technical degree + 8+ years of clinical research/project management experience

Bachelor's degree + 4+ years of relevant experience; or

Master's or PhD degree + 2+ years of relevant experience

Tools

Wrike

MS Project

REDCap

Job description

COMPENSATION & BENEFITS

• Competitive salary of $90,000 - $100, 000 per year, commensurate with experience plus benefits
• Full-time, 40 hours per week
• Onsite position
• Benefits include health insurance, paid parental leave, PTO, and 401k with 5% employer match after 1 year

POSITION SUMMARY

The Clinical Research Core at The Buck Institute is seeking an experienced and motivated Clinical Project Manager to lead the day-to-day execution of two complex, multi-component clinical research studies, TIME and BETA, within a larger federally funded research program. These studies aim to advance our understanding of personalized medicine.

The Clinical Project Manager will oversee study operations, staff, regulatory compliance, data and biospecimen quality, timelines, budgets, and coordination with internal and external stakeholders. This role will work closely with Clinical Research Co-Directors Dr. Newman, MD, PhD, a practicing geriatrician, and Dr. Brianna Stubbs, PhD, who brings more than 10 years of clinical research experience.

Clinical research is a rapidly growing area at the Buck. Because the team is small, this position offers a high degree of ownership and visibility, combining leadership responsibility with direct involvement in study planning, conduct, and reporting.

KEY RESPONSIBILITIES

Trial Leadership & Execution

• Lead day-to-day execution of assigned clinical trials, ensuring compliance with study protocols, GCP, ICH Guidelines, and Buck Institute Clinical Research SOPs.
• Manage study collaborators and vendors, ensuring services and deliverables meet study needs and timelines.
• Monitor participant enrollment, study milestones, and team capacity, and flag timeline, budget, or operational risks to Clinical Research Core leadership.
• Coordinate protocol amendments, study close-out activities, team meetings, action items, and follow-up on deliverables.

Regulatory, Data & Compliance

• Maintain IRB compliance, including continuing reviews, amendments, and required regulatory documentation.
• Oversee timely and accurate data entry, query resolution, and good documentation practices across data capture systems.
• Oversee safety reporting and escalation for adverse events, serious adverse events, adverse events of special interest, and protocol deviations.
• Ensure biospecimens, study equipment, supplies, and other physical resources are organized, tracked, maintained, and available in accordance with protocol requirements.
• Protect participant health information and sponsor-confidential information.

Staff Management & Training

• Lead, mentor, train, and support Clinical Research Associates, ensuring training, delegation, workload distribution, and back-up coverage are appropriately managed and documented.
• Coordinate participant, staff, medical, room, equipment, and other clinical resource scheduling, adjusting plans as needed when priorities shift.
• Communicate study progress, needs, and risks to internal and external stakeholders and collaborate with study medical staff to resolve operational or participant review questions.
• Promote respect for cultural diversity and support culturally competent, multilingual recruitment.

QUALIFICATIONS

Education & Experience

One of the following:

• High school diploma/technical degree plus 8+ years of clinical research/project management experience in biomedical or clinical research;
• Bachelor's degree plus 4+ years of relevant experience; or
• Master's or PhD degree plus 2+ years of relevant experience.

Required Skills

• Strong organization and ability to manage concurrent studies and priorities.
• Proactive problem-solving, initiative, and consistent follow-through.
• Prior supervisory and/or team leadership experience.
• Strong written, verbal, and interpersonal communication skills.
• Strong attention to deadlines and budget guidelines.
• Experience preparing or submitting IRB protocols, amendments, or continuing reviews.
• Clinical skills/background sufficient to train, mentor, and oversee quality for staff performing clinical procedures.

Desired but not required

• Professional certification such as PMP, ACRP-CP, SOCRA CCRP, or equivalent.
• Experience with project management software such as Wrike, MS Project.
• Experience with EDC/data capture systems such as REDCap.
• Phlebotomy certification/experience.
• Experience in a nonprofit or academic clinical research setting.

ABOUT US

The Buck Institute is an independent, nonprofit research institution in Marin County, California, focused on extending human healthspan—the healthy years of life. Our scientists work across disciplines to understand and target aging, a major risk factor for diseases including Alzheimer’s, Parkinson’s, cancer, macular degeneration, heart disease, and diabetes. Our goal is to help people live better, longer.

Applicants must be authorized to work for any employer in the U.S. We are unable to sponsor or take over sponsorship of an employment visa at this time.

The Buck Institute is an equal opportunity employer and welcomes candidates from diverse identities, experiences, and backgrounds.