Clinical Laboratory Scientist (CLS)

SeqMatic LLC; Fremont (CA); On-site; USD 90,000 - 120,000; Full time

Job summary

SeqMatic LLC in Fremont, CA is seeking a Clinical Laboratory Scientist (CLS) to join our CLIA-certified operations, performing high-complexity molecular testing and supporting clinical trial workflows. The ideal candidate holds a California CLS license, a Bachelor’s or Master’s in a related field, 2+ years in a clinical lab or research setting, and familiarity with NGS, CLIA/CAP, and GCP practices.

You will work with Illumina instruments, participate in documentation, quality assurance, and

Qualifications

• Valid California CLS license required.
• Bachelor’s or Master’s degree in Clinical Laboratory Science, Molecular Biology, or related field.
• 2+ years of experience in a clinical laboratory or clinical research setting.
• Familiarity with NGS workflows and clinical assay validation preferred.
• Strong understanding of CLIA/CAP regulations and GCP guidelines.
• Excellent communication and organizational skills.
• Must be legally authorized to work in the USA.

Responsibilities

• Conduct high-complexity molecular testing in CLIA/CAP environment.
• Perform sample QC and library QC.
• Operate and maintain Illumina sequencers.
• Review and validate clinical data and lab results.
• Collaborate with sponsors and internal teams to ensure protocol adherence.
• Maintain detailed documentation and contribute to regulatory submissions.
• Assist in development/validation of new clinical assays.
• Participate in QA and continuous improvement initiatives.
• Maintain updated knowledge of lab methods.
• Follow GLP: keep workspace clean and organized.
• Update SOPs to reflect current practices.
• Perform quality control procedures for data accuracy.
• Assist teammates with daily tasks

Skills

Molecular diagnostics

NGS workflows

CLIA/CAP regulations

GCP guidelines

Communication skills

Organizational skills

GLP

Illumina sequencing

Education

Bachelor’s or Master’s degree in CLS/Molecular Biology/related

Tools

Illumina sequencers

Job description

Clinical Laboratory Scientist (CLS)

SeqMatic LLC Fremont, California, United States

About this position

SeqMatic is a CLIA-licensed, CAP-accredited contract research organization (CRO) specializing in next-generation sequencing (NGS), multiomics, and histopathology services. Founded by former Illumina R&D scientists, we support clinical and translational research through high-quality laboratory services and personalized support.

Position Summary:
We are seeking a Clinical Laboratory Scientist with a valid California CLS license to join our clinical operations team. This role involves supporting clinical trial workflows, ensuring regulatory compliance, and performing high-complexity testing in a CLIA-certified environment. The ideal candidate will have a strong background in molecular diagnostics and a passion for advancing clinical research.

Key Responsibilities:

• Conduct high-complexity molecular testing, including NGS-based assays, in compliance with CLIA/CAP regulations.
• Perform sample QC and library QC.
• Operate and maintain Illumina sequencers.
• Review and validate clinical data and laboratory results for accuracy and completeness.
• Collaborate with clinical trial sponsors and internal teams to ensure protocol adherence.
• Maintain detailed documentation and contribute to regulatory submissions.
• Assist in the development and validation of new clinical assays.
• Participate in quality assurance and continuous improvement initiatives.
• Responsible for maintaining updated understanding and knowledge of methods performed in the lab
• Follows GLP (good laboratory practice): maintain clean and organized work space
• Participates in the updating of departmental standard operating procedures to accurately reflect the current practices.
• Performs quality control procedures to ensure accuracy of clinical data (if applicable)
• Assists teammates in completing daily tasks

Qualifications:

• Valid California Clinical Laboratory Scientist (CLS) license.
• Bachelor’s or Master’s degree in Clinical Laboratory Science, Molecular Biology, or related field.
• 2+ years of experience in a clinical laboratory or clinical research setting.
• Familiarity with NGS workflows and clinical assay validation preferred.
• Strong understanding of CLIA/CAP regulations and GCP guidelines.
• Excellent communication and organizational skills.
• Must be legally authorized to work in the USA.