Clinical Laboratory Scientist (CLS)

SeqMatic LLC.; Fremont (CA); On-site; USD 90,000 - 130,000; Full time

Job summary

SeqMatic LLC is seeking a Clinical Laboratory Scientist with a valid California CLS license to join our clinical operations team in Fremont, CA. You will support clinical trial workflows, ensure regulatory compliance, and perform high-complexity testing in a CLIA-certified environment.

The ideal candidate has a strong background in molecular diagnostics and a passion for advancing clinical research. You will work with Illumina sequencers, participate in protocol adherence, and contribute to

Qualifications

• Valid California CLS license.
• Bachelor’s or Master’s degree in CLS, Molecular Biology or related field.
• 2+ years of experience in clinical lab or clinical research.
• Familiarity with NGS workflows and clinical assay validation preferred.
• Strong understanding of CLIA/CAP regulations and GCP guidelines.

Responsibilities

• Conduct high-complexity molecular testing, including NGS-based assays, in CLIA/CAP-compliant environment.
• Perform sample QC and library QC.
• Operate and maintain Illumina sequencers.
• Review and validate clinical data and lab results for accuracy and completeness.
• Collaborate with sponsors and internal teams to ensure protocol adherence.
• Maintain detailed documentation and contribute to regulatory submissions.
• Assist in development and validation of new clinical assays.
• Participate in quality assurance and continuous improvement initiatives.
• Maintain updated knowledge of lab methods and GLP practices.
• Update departmental SOPs to reflect current practices.

Skills

Molecular diagnostics

Regulatory compliance

Quality assurance

Communication

Organizational skills

Education

Bachelor’s or Master’s degree in Clinical Laboratory Science or Molecular Biology

Tools

Illumina sequencers

Job description

SeqMatic is a CLIA-licensed, CAP-accredited contract research organization (CRO) specializing in next-generation sequencing (NGS), multiomics, and histopathology services. Founded by former Illumina R&D scientists, we support clinical and translational research through high-quality laboratory services and personalized support.

Position Summary:

We are seeking a Clinical Laboratory Scientist with a valid California CLS license to join our clinical operations team. This role involves supporting clinical trial workflows, ensuring regulatory compliance, and performing high-complexity testing in a CLIA-certified environment. The ideal candidate will have a strong background in molecular diagnostics and a passion for advancing clinical research.

Key Responsibilities:

• Conduct high-complexity molecular testing, including NGS-based assays, in compliance with CLIA/CAP regulations.
• Perform sample QC and library QC.
• Operate and maintain Illumina sequencers.
• Review and validate clinical data and laboratory results for accuracy and completeness.
• Collaborate with clinical trial sponsors and internal teams to ensure protocol adherence.
• Maintain detailed documentation and contribute to regulatory submissions.
• Assist in the development and validation of new clinical assays.
• Participate in quality assurance and continuous improvement initiatives.
• Responsible for maintaining updated understanding and knowledge of methods performed in the lab
• Follows GLP (good laboratory practice): maintain clean and organized work space
• Participates in the updating of departmental standard operating procedures to accurately reflect the current practices.
• Performs quality control procedures to ensure accuracy of clinical data (if applicable)
• Assists teammates in completing daily tasks

Qualifications:

• Valid California Clinical Laboratory Scientist (CLS) license.
• Bachelor's or Master's degree in Clinical Laboratory Science, Molecular Biology, or related field.
• 2+ years of experience in a clinical laboratory or clinical research setting.
• Familiarity with NGS workflows and clinical assay validation preferred.
• Strong understanding of CLIA/CAP regulations and GCP guidelines.
• Excellent communication and organizational skills.
• Must be legally authorized to work in the USA.