Clinical Imaging Scientist

Aktis Oncology; United States; On-site; USD 110,000 - 170,000; Full time

Job summary

Aktis Oncology, Inc. is a clinical-stage oncology company focused on expanding radiopharmaceuticals. The Clinical Imaging Scientist will support imaging and PK data collection, dosimetry analysis, and work with Medical Physics and Clinical Operations to advance multiple programs.

Experience in PET/CT, SPECT/CT, and radiopharmaceutical handling is required. The role involves collaboration with CROs and sites, contributing to study manuals, regulatory documents, and publications.

Qualifications

• Bachelor of Science in a life science with emphasis on nuclear medicine or related field.
• NMTCB/ARRT certification in Nuclear Medicine or equivalent preferred.
• MS or higher degree in related field is a plus.
• Minimum years of experience in clinical nuclear medicine and/or imaging trials.

Responsibilities

• Lead clinical image acquisition, reconstruction, and processing workflows for PET/CT and SPECT/CT.
• Support pharmacokinetic modeling and patient-specific dosimetry data processing.
• Maintain knowledge of radiological imaging infrastructure and IHE/PACS systems.
• Assist radiopharmaceutical handling, dose calibration, and safety in clinical studies.
• Collaborate with multidisciplinary teams to ensure data quality and regulatory compliance.

Skills

Analytical problem-solving

Verbal and written communication

Multi-tasking

Team collaboration

Travel readiness

Microsoft Office

Python scripting

Education

B.S. in life sciences or related

NMTCB/ARRT Nuclear Medicine certification

MS or equivalent in related field (preferred)

Tools

MIM

PACS

Dosimetry software

Job description

Aktis Oncology, Inc. is a clinical-stage oncology company focused on expanding the breakthrough potential of targeted radiopharmaceuticals to large patient populations, including those not addressed by existing platform technologies. Aktis’ most-advanced program, AKY-1189, is a miniprotein radioconjugate targeting Nectin-4, with multi-indication potential across multiple tumor types, including locally advanced or metastatic urothelial cancer, breast cancer, non-small cell lung cancer, colorectal cancer, cervical cancer, and head and neck cancer. Aktis’ second pipeline program, AKY-2519, is a miniprotein radioconjugate targeting B7-H3 expressing tumors, including prostate, lung and other solid tumors. Aktis has a strategic collaboration with Eli Lilly and Company to leverage its miniprotein platform to develop novel radioconjugates outside of Aktis’ proprietary pipeline.

The Clinical Imaging Scientist will support imaging and pharmacokinetic (PK) data collection activities to enable image analysis and dosimetry analysis across our clinical programs. This position reports to the Head of Clinical Sciences and operates within the Clinical Development team, partnering closely with Medical Physics, Clinical Operations, Clinical Pharmacology, and external clinical site and CROs. A successful candidate will bring deep nuclear medicine imaging expertise and a scientific, research-oriented mindset to a small, fast-moving team. The role is well suited to senior nuclear medicine technologists, clinical application specialists, and imaging scientists with industry experience.

RESPONSIBILITIES

Clinical imaging and equipment operations

• Provide subject matter expertise to internal and external stakeholders on clinical image acquisition, reconstruction, and processing workflows for PET/CT and SPECT/CT, with working familiarity in diagnostic imaging.
• Assist with in-house processing of clinical imaging and dosimetry data to support pharmacokinetic modeling and patient-specific dosimetry.
• Maintain working knowledge of modern radiological imaging infrastructure, including nuclear imaging technology, DICOM, PACS, IHE profiles, image processing, and advanced visualization tools.

Radiopharmaceutical preparation and administration

• Provide support to clinical site staff and investigators on preparation, administration, and waste management of imaging and therapeutic radiopharmaceuticals.
• Respond to radiation safety questions and concerns from clinical sites regarding the use of diagnostic and therapeutic radiopharmaceuticals and associated patient precautions.
• Serve as a subject matter expert on radiopharmaceutical handling, dose calibration, and administration workflows for internal and external stakeholders.

Quality control and regulatory compliance

• Assist in the development and adherence to clinical study documents (e.g. Imaging Manual, Dosimetry Manual, etc).
• Maintain a curated archive of imaging-related data for ongoing and completed trials, ensuring quality, traceability, and audit-readiness.
• Support imaging-related aspects of clinical studies in accordance with the clinical protocol, study manuals and plans, and timelines, ensuring quality in accordance with GCP and ICH guidelines.

Collaboration and Communication

• Collaborate with multidisciplinary clinical teams, manufacturing personnel, and regulatory bodies to ensure high-quality patient care and compliance with industry standards.
• Collaborate with clinical operations in the oversight, conduct, and management of imaging-related aspects of clinical studies.
• Provide support for clinical data review and assist in the generation of clinical research reports, regulatory documents, abstracts, posters, and publications.
• Clearly articulate the role and impact of molecular imaging on decision-making within drug discovery and development to scientific, clinical, and operational audiences.

QUALIFICATIONS

• Bachelor of Science degree from an accredited institution with a life science focus (e.g. physics, medical physics, health physics, biomedical engineering, radiological sciences, or equivalent).
• Certification by the Nuclear Medicine Technology Certification Board (NMTCB), American Registry of Radiologic Technologists (ARRT) in Nuclear Medicine, or equivalent professional certification in molecular imaging preferred.
• Additional training in radiation safety and/or advanced qualifications (MS or equivalent) in related field preferred.

EXPERIENCE

• Minimum of 5 years of clinical experience in nuclear medicine or related field.
• 2-5 years of experience working in clinical trials for investigational diagnostic or therapeutic radiopharmaceuticals preferred.
• Extensive hands-on experience with common medical imaging workstations, image analysis platforms (e.g. MIM), PACS, and dosimetry software applications from multiple different vendors.
• Scientific expertise in quantitative SPECT and PET imaging, including patient setup, acquisition, reconstruction, calibration, and image transfer workflows.
• Experience with radioactive material licensing and familiarity with NRC/Agreement States radioactive material license amendment process preferred, and Radiation Safety Officer responsibilities a plus.

SKILLS & ATTRIBUTES

• Excellent technical and analytical problem-solving skills, with keen attention to detail and a quantitative mindset.
• Self-motivated and exceptional verbal and written communication skills, with the ability to translate technical content clearly to a mixed scientific, clinical, and operational audience.
• Ability to multi-task and work effectively as part of a team or independently on tasks in a fast-paced small biotech environment.
• Comfortable working in a non-clinical environment as part of a cross-functional, collaborative, and research-oriented clinical development team.
• Willingness to travel as needed for scientific meetings and supporting clinical development activities (~10-20%).
• Proficiency with common business software tools (e.g Microsoft office). Scripting experience in Matlab or python is a plus.

Aktis Oncology is an Equal Opportunity Employer and does not discriminate on the basis of race, religion, color, sex, gender identity or expression, sexual orientation, age, disability, national origin, veteran status, or any other basis covered by appropriate law. Aktis Oncology is committed to promoting and maintaining a work environment in which all applicants, employees, and other individuals are treated with dignity and respect free from unlawful harassment, discrimination, or retaliation.