Imaging Clinical Research Physician

Scorpion Therapeutics; Indianapolis (IN); On-site; USD 180,000 - 260,000; Full time

Job summary

Scorpion Therapeutics seeks a physician-scientist to lead integrated clinical development programs for diagnostic radiopharmaceuticals across oncology, immunology and cardiovascular diseases. You will define strategies, endpoints and imaging criteria for early and late phases, while serving as a scientific expert in PET, SPECT, CT and MRI modalities.

The role requires MD with board eligibility/certification, 5+ years in clinical development (3+ in industry), and strong GCP/regulatory

Qualifications

• MD or equivalent with board eligibility/certification.
• Minimum 5 years clinical development experience; minimum 3 years industry.
• Tracer development experience; oncology, immunology and/or cardiology experience highly preferred.

Responsibilities

• Lead the design and execution of integrated clinical development programs for diagnostic radiopharmaceuticals across multiple disease areas.
• Define clinical strategies, endpoints, patient populations, and imaging criteria for each phase of development.
• Design studies to evaluate diagnostic accuracy, optimal imaging timing, and biomarkers for patient stratification.
• Serve as a scientific expert in molecular imaging modalities (PET, SPECT, CT, MRI) including inflammatory and disease-activity imaging; theranostics a plus.
• Analyze and interpret molecular imaging data (tumor localization, biodistribution, dosimetry, longitudinal response).
• Evaluate imaging performance metrics (sensitivity, specificity, SUVs, tumor-to-background ratios).
• Provide strategic input into advanced image analysis methods (development, validation, quantitative evaluation).
• Apply disease biology knowledge to guide imaging strategy.
• Collaborate with physicians, scientists, medical physicists, imaging operations, and analytics teams.
• Lead cross-functional projects and coordinate with CROs, academics, software developers, Scanner manufacturers.
• Evaluate emerging imaging advances (modeling, AI) for clinical programs.
• Author/review clinical and regulatory documents and contribute to manuals.
• Communicate findings via presentations, abstracts, and publications.

Skills

Tracer development

GCP/regulatory

Communication/collaboration

English fluency

Imaging modalities

Travel willingness

Education

MD (or equivalent) with board eligibility/certification

Tools

PET

SPECT

CT

MRI

Job description

Key Responsibilities

• Lead the design and execution of integrated clinical development programs for diagnostic radiopharmaceuticals in oncology, immunology and cardiovascular diseases across early and late-phase development.


• Define clinical strategies, endpoints, patient populations, and imaging criteria for each phase of development.


• Design studies to evaluate diagnostic accuracy, optimal imaging timing, patient selection biomarkers, and comparative performance vs. standard-of-care imaging.


• Serve as a scientific expert in molecular imaging modalities (PET, SPECT, CT, MRI), including inflammatory and disease-activity imaging; oncology focus and emerging theranostic platforms a plus.


• Analyze and interpret molecular imaging data (tumor localization, tracer biodistribution, dosimetry, longitudinal response); evaluate imaging biomarkers for stratification and monitoring.


• Evaluate imaging performance metrics (sensitivity, specificity, SUVs, tumor-to-background ratios).


• Provide strategic input into advanced image analysis methods (development, validation, quantitative evaluation).


• Apply disease biology knowledge to guide diagnostic imaging scientific strategy.


• Collaborate with physicians, scientists, medical physicists, imaging operations, and advanced image analysis teams.


• Lead cross-functional projects and coordinate with external partners (CROs, academics, software developers, scanner manufacturers).


• Evaluate emerging imaging advances (modeling, AI) and drive application in clinical programs.


• Author/review clinical and regulatory documents (Investigator’s Brochures, protocols/amendments, clinical study reports, regulatory briefings) and contribute to technical manuals.


• Communicate findings via presentations, abstracts, and peer-reviewed publications.


• Other duties as assigned.

Basic Requirements

• Medical Doctor: board eligible/certified in relevant specialty (or completed comparable post-medical clinical training); non-U.S. trained must meet LCME requirements.


• Minimum 5 years clinical development experience; minimum 3 years industry experience.

Additional Skills/Preferences

• Tracer development experience; oncology, immunology and/or cardiology experience highly preferred.


• Strong problem-solving skills; anticipate systemic issues and prevent recurrence.


• Familiarity with Good Clinical Practice (GCP) and regulatory requirements.


• Ability to balance scientific and business priorities; strong communication/collaboration/organizational/influencing skills.


• Fluency in written/spoken English.


• Travel estimated 10–15%.