Director, Immunology - CRO

Michael Page; Boston (MA); À distance; USD 300 000 - 420 000; Plein temps

Avantages offerts par ce poste

Remote with travel

Competitive compensation package

Long-term incentives

Résumé du poste

MPI is seeking an experienced immunology leader to guide discovery, translational and preclinical programs. The role combines deep disease biology with cross-functional leadership to support informed decisions and advancement of novel therapies.

The candidate will engage with clients, lead biomarker and translational strategies, and collaborate across toxicology, bioanalysis, DMPK and regulatory teams. Remote with travel, Boston area preferred.

Qualifications

• Ph.D. in Immunology or closely related field.
• 15+ years in biopharmaceutical discovery, translational and preclinical development.
• Expertise in immunology, inflammation, autoimmune biology and immune-mediated disorders.
• Strong target identification, validation, lead optimization and candidate selection.
• Experience translating preclinical data to clinical development plans.

Responsabilités

• Serve as senior scientific advisor for immunology-focused discovery and development.
• Lead client discussions on disease biology, target selection and translational plans.
• Guide pharmacology strategies, biomarkers and mechanism-of-action validation.
• Evaluate efficacy, PK/PD, safety and translational datasets.
• Support candidate advancement through preclinical and IND-enabling stages.
• Collaborate with toxicology, pathology, bioanalysis, DMPK and regulatory teams.
• Identify risks, propose mitigations, and align stakeholders around goals.
• Contribute to autoimmune, inflammatory and immune-mediated program expertise.

Connaissances

Immunology leadership

Cross-functional leadership

Scientific communication

StrategicDrugDevelopment

Client-facing collaboration

Formation

Ph.D. in Immunology

Description du poste

Seeking an experienced immunology leader to provide scientific and strategic guidance across discovery, translational, and preclinical development programs. This client-facing position combines deep disease biology expertise with cross-functional leadership to support informed decision-making and successful advancement of novel therapies.

Our client is a global, multibillion dollar renowned renown CRO supporting drug discovery and development programs. The organization works with major emerging biotech's and top 20+ major Big Pharma companies to support a broad range of therapeutic areas and advanced treatment modalities.

Description

• Serve as a senior scientific advisor for immunology-focused drug discovery and development programs.
• Lead strategic discussions with clients regarding disease biology, target selection, and translational development plans.
• Provide guidance on pharmacology strategies, biomarker approaches, and mechanism-of-action validation.
• Evaluate integrated datasets spanning efficacy, PK/PD, safety, biomarker, and translational research findings.
• Support candidate selection and advancement decisions through preclinical and IND-enabling stages.
• Collaborate with multidisciplinary teams including toxicology, pathology, bioanalysis, DMPK, and regulatory experts.
• Identify scientific risks, propose mitigation strategies, and align stakeholders around development objectives.
• Contribute expertise across autoimmune, inflammatory, and immune-mediated disease programs.

Profile

• Ph.D. in Immunology or a closely related life sciences discipline.
• 15+ years of biopharmaceutical industry experience within discovery, translational research, and preclinical development.
• Demonstrated expertise in immunology, inflammation, autoimmune disease biology, and immune-mediated disorders.
• Strong understanding of target identification and validation, lead optimization, and candidate selection.
• Experience developing biomarker strategies and translating preclinical findings into clinical development plans.
• Knowledge of immunogenicity assessment, immune activation and suppression pathways, and translational pharmacology.
• Proven ability to communicate complex scientific concepts to internal and external stakeholders.
• Track record of cross-functional leadership and influencing strategic decisions in a matrixed environment.
• Familiarity with biologics, small molecules, multispecific antibodies, cytokine-based therapies, cell and gene therapies, and emerging therapeutic platform

Job Offer

• Fully remote with occasional travel. Boston area is preferred but flexible on location.
• Opportunity to influence high-profile immunology programs from early discovery through IND-enabling development.
• Significant client exposure and strategic leadership responsibilities.
• Collaboration with world-class scientific and technical experts.
• Access to innovative therapeutic programs and emerging technologies.
• Competitive compensation package, including potential bonus and long-term incentives.
• Flexible work arrangements and a collaborative, mission-driven culture.
• Clear opportunity to contribute to therapies with the potential to improve patient outcomes globally.
  

Seeking an experienced immunology leader to provide scientific and strategic guidance across discovery, translational, and preclinical development programs. This client-facing position combines deep disease biology expertise with cross-functional leadership to support informed decision-making and successful advancement of novel therapies.

Client Details

Our client is a global, multibillion dollar renowned renown CRO supporting drug discovery and development programs. The organization works with major emerging biotech's and top 20+ major Big Pharma companies to support a broad range of therapeutic areas and advanced treatment modalities.

Description

• Serve as a senior scientific advisor for immunology-focused drug discovery and development programs.
• Lead strategic discussions with clients regarding disease biology, target selection, and translational development plans.
• Provide guidance on pharmacology strategies, biomarker approaches, and mechanism-of-action validation.
• Evaluate integrated datasets spanning efficacy, PK/PD, safety, biomarker, and translational research findings.
• Support candidate selection and advancement decisions through preclinical and IND-enabling stages.
• Collaborate with multidisciplinary teams including toxicology, pathology, bioanalysis, DMPK, and regulatory experts.
• Identify scientific risks, propose mitigation strategies, and align stakeholders around development objectives.
• Contribute expertise across autoimmune, inflammatory, and immune-mediated disease programs.

Profile

• Ph.D. in Immunology or a closely related life sciences discipline.
• 15+ years of biopharmaceutical industry experience within discovery, translational research, and preclinical development.
• Demonstrated expertise in immunology, inflammation, autoimmune disease biology, and immune-mediated disorders.
• Strong understanding of target identification and validation, lead optimization, and candidate selection.
• Experience developing biomarker strategies and translating preclinical findings into clinical development plans.
• Knowledge of immunogenicity assessment, immune activation and suppression pathways, and translational pharmacology.
• Proven ability to communicate complex scientific concepts to internal and external stakeholders.
• Track record of cross-functional leadership and influencing strategic decisions in a matrixed environment.
• Familiarity with biologics, small molecules, multispecific antibodies, cytokine-based therapies, cell and gene therapies, and emerging therapeutic platform

Job Offer

• Fully remote with occasional travel. Boston area is preferred but flexible on location.
• Opportunity to influence high-profile immunology programs from early discovery through IND-enabling development.
• Significant client exposure and strategic leadership responsibilities.
• Collaboration with world-class scientific and technical experts.
• Access to innovative therapeutic programs and emerging technologies.
• Competitive compensation package, including potential bonus and long-term incentives.
• Flexible work arrangements and a collaborative, mission-driven culture.
• Clear opportunity to contribute to therapies with the potential to improve patient outcomes globally.
  

Desired Skills and Experience

Ph.D. immunology expert with 15+ years of biopharmaceutical industry experience in discovery, translational research, and preclinical/IND-enabling development.

Strong judgment in target validation, lead optimization, candidate selection, translational biomarker strategy, immunogenicity, immune activation/suppression, and clinical relevance of preclinical data.

MPI does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity or expression, national origin, age, disability, veteran status, marital status, or based on an individual's status in any group or class protected by applicable federal, state or local law. MPI encourages applications from minorities, women, the disabled, protected veterans and all other qualified applicants.