Cell Line Development Scientist

Demeetra Agbio Inc.; Lexington (KY); On-site; USD 70,000 - 90,000; Full time

Job summary

Valid8 Financial, Inc. is seeking a highly motivated Cell Line Development Scientist to advance next-generation gene editing technologies. You will be instrumental in developing engineered CHO cell lines and optimizing processes in a fast-paced environment.

The ideal candidate will possess an MS or PhD in related fields and experience with CHO cell culture and molecular biology techniques. This full-time role offers significant hands-on impact in a collaborative setting.

Qualifications

• MS or PhD in biology, biochemistry, biotechnology, or related field required.
• Demonstrated proficiency in molecular biology and vector construction.
• Ability to thrive in a high-expectation, fast-moving environment.

Responsibilities

• Execute CHO cell culture processes across shake flasks and spin tube fed-batch formats.
• Perform transfection, selection, single-cell cloning, and clone characterization workflows.
• Support upstream development with high attention to process consistency and data integrity.

Skills

Molecular biology and vector construction

Suspension CHO cell culture

Transfection & selection workflows

Shake flask, spin tube, and deep-well plate fed-batch processes

Single-cell cloning

Titer determination and standard downstream quality assessments

Analytical techniques (HPLC, LC/MS, CE)

Education

MS or PhD in biology, biochemistry, biotechnology, or related field

Job description

Demeetra is seeking a highly motivated Cell Line Development Scientist to join our fast-paced team advancing next-generation gene editing technologies in bioproduction. This role is designed for someone who is eager, hands‑on, detail‑driven, and experienced enough to contribute with minimal onboard training. The successful candidate must be driven by a culture of excellence and ready for intense, high‑expectation, hands‑on CLD workflows, bringing industry experience that enables them to contribute at a high level from day one, ideally in a CRO or CDMO setting.

About the Role

You will be a key contributor in developing engineered CHO cell lines and optimizing upstream processes that support Demeetra’s cutting‑edge gene editing platforms. This position is ideal for recent graduates (MS or PhD) and are eager to take ownership of experimental design, workflow execution, and timeline‑driven deliverables.

Responsibilities

• Execute CHO cell culture processes across shake flasks and spin tube fed‑batch formats
• Perform transfection, selection, single‑cell cloning, and clone characterization workflows
• Support upstream development with high attention to process consistency and data integrity
• Vector design and molecular biology
• Run titer and basic downstream quality assays to assess productivity and cell line performance, analytical experience (HPLC) is a plus.
• Collaborate cross‑functionally to implement advanced gene editing technologies in CLD
• Contribute to workflow design, documentation, and continuous process improvement
• Maintain a culture of excellence, accountability, and meeting or exceeding timelines

Required Qualifications

• MS or PhD in biology, biochemistry, biotechnology, or related field required
• Demonstrated proficiency in:
  • Molecular biology and vector construction
  • Suspension CHO cell culture
  • Transfection & selection workflows
  • Shake flask, spin tube, and deep‑well plate fed‑batch processes
  • Single‑cell cloning
  • Titer determination and standard downstream quality assessments
  • Analytical techniques such as HPLC, LC/MS, and/or CE.
• Ability to thrive in a high‑expectation, fast‑moving environment
• Strong communication, organization, and documentation skills

Why Join Demeetra?

This is an opportunity to join a growing company at the forefront of gene editing applied to cell line development and bioprocessing. You will have significant hands‑on impact, work with advanced technologies, and be part of an intensely collaborative and rewarding environment.

Employment Type

Full‑time