Biotherapeutics Expression Scientist I - CHO & Automation

AbbVie Inc.; North Chicago (IL); On-site; USD 120,000 - 170,000; Full time

Benefits offered by this job

Paid time off

Medical/dental/vision insurance

401(k) to eligible employees

Short-term incentive programs

Job summary

AbbVie Inc. in North Chicago, IL is seeking an experienced protein expression scientist to join a fast-paced CHO cell culture group supporting therapeutic protein discovery and development.

The role focuses on engineering multispecific biologics, optimizing expression, and advancing data digitization and automation. Strong biology background with CHO experience and leadership are valued for cross-functional collaboration.

Qualifications

• Bachelors or Masters in biology/biochemistry or related field.
• 5+ years (BS) or 2+ years (MS) experience in CHO cell culture and protein production.
• Experience with CHO-based expression and cryopreservation.

Responsibilities

• Generation, expression, and screening of stable CHO cell lines expressing multispecific biologics.
• Process development and optimization for fed-batch bioreactor and shake flask expressions.
• Handling stable CHO pool cell lines including thaw, culture, expression and cryopreservation.
• Apply targeted integration using FACS-based single-cell sorting for screening.
• Characterization of copy number and mRNA transcript levels using ddPCR and related tools.
• Implement and leverage automation platforms and high-throughput workflows to increase efficiency.
• Contribute to data digitization efforts, including electronic data capture, analysis, and concise reporting.
• Work independently on the design, execution, and interpretation of experimental results.

Skills

CHO cell culture

Data analysis

FACS

Wave bioreactors

Education

Bachelor's or Master’s in biology/biochemistry

Tools

FACS

ddPCR

Wave bioreactors

Automation platforms

Job description

AbbVie Inc. in North Chicago, IL is seeking an experienced protein expression scientist to join a fast-paced CHO cell culture group supporting therapeutic protein discovery and development.

The role focuses on engineering multispecific biologics, optimizing expression, and advancing data digitization and automation. Strong biology background with CHO experience and leadership are valued for cross-functional collaboration.