Biotech Finance Ops Lead: Inventory & Costing

Nautilus Biotechnology; San Carlos (CA); On-site; USD 110,000 - 150,000; Full time

Job summary

Nautilus Biotechnology seeks an Accounting Operations Manager to bridge operations and finance, owning inventory accuracy, standard costing, and cost analysis for reagent kits, flow cells, and instrument components. This role partners with operations, supply chain, and leadership to enable scalable financial reporting.

The position is hands-on in a fast-paced biotech environment, reporting to the Corporate Controller, and driving close processes, ERP controls, and cost optimization across

Qualifications

• 6+ years of experience in manufacturing finance, cost accounting, inventory accounting, or related roles.
• Experience in biotechnology or regulated manufacturing environments preferred.
• Strong understanding of inventory accounting, standard costing, variance analysis, and operational controls.
• Experience with ERP systems such as NetSuite, SAP, or similar (NetSuite preferred).
• Advanced Excel / financial modeling capabilities.
• Ability to work cross-functionally with operations, procurement, and leadership.
• Comfortable operating in a fast-paced, early-stage biotech environment.

Responsibilities

• Own month-end inventory close processes across raw materials, work-in-process, and finished goods (reagent kits, flow cells, and instrument components).
• Ensure timely and accurate closure of purchase orders, receipts, inventory transfers, and sales orders in NetSuite.
• Reconcile inventory movements, adjustments, yield loss, and scrap across product lines.
• Partner with operations and supply chain teams to improve ERP transaction discipline and inventory accuracy.
• Maintain inventory subledger integrity and support reconciliation to the general ledger.
• Review inventory discrepancies, negative inventory balances, and operational exceptions.
• Support implementation and optimization of NetSuite workflows and inventory controls as Nautilus scales toward commercialization.
• Build and maintain standard costing methodologies for raw materials, packaging, labor, freight, contract manufacturing, and cold-chain storage.
• Develop and maintain product-level and batch-level COGS models for reagent kits, flow cells, and instrumentation.
• Create labor, freight, and materials standards and perform variance analysis against actuals.
• Analyze purchase price variances, manufacturing variances, and gross margin drivers.
• Support pricing decisions and operational improvement initiatives through financial analysis.
• Partner with operations to improve yields, throughput, and cost efficiency.
• Build operational finance KPIs and reporting dashboards for inventory and cost performance.
• Support forecasting, budgeting, and financial planning activities related to inventory and cost of goods sold.
• Assist with audit readiness, inventory procedures, and SEC/investor reporting; maintain SOX 404 documentation.
• Collaborate with leadership on scaling infrastructure as the company grows.

Skills

Inventory accounting

Cost accounting

ERP systems

Financial analysis

Excel

SOX controls

Cross-functional collaboration

Tools

NetSuite

SAP

Job description

Nautilus Biotechnology seeks an Accounting Operations Manager to bridge operations and finance, owning inventory accuracy, standard costing, and cost analysis for reagent kits, flow cells, and instrument components. This role partners with operations, supply chain, and leadership to enable scalable financial reporting.

The position is hands-on in a fast-paced biotech environment, reporting to the Corporate Controller, and driving close processes, ERP controls, and cost optimization across