Bioprocess Research Associate — Fermentation Platform Builder

Flagship Pioneering; Watertown (MA); On-site; USD 65,000 - 94,000; Full time

Benefits offered by this job

Healthcare coverage

Annual incentive program

Retirement benefits

Job summary

Flagship Pioneering in Cambridge, MA is seeking a Research Associate I/II to support the development and optimization of microbial fermentation processes for recombinant protein production. The role is hands-on and involves building a fermentation platform within a fast-paced startup setting.

You will operate shake flasks and bench-scale bioreactors, prepare media, monitor runs, and collaborate with strain engineering, downstream, and analytical teams to drive scalable process development and

Qualifications

• Hands-on experience in microbial fermentation or related laboratory environments.
• Experience operating and maintaining bench-scale bioreactors for microbial fermentation workflows, with strong understanding of aseptic technique and microbial culture handling.
• Strong organizational and documentation skills.
• Ability to independently execute experiments and troubleshoot routine process issues.

Responsibilities

• Operate, monitor, and troubleshoot shake flask and bench-scale microbial fermentation systems, executing batch and fed-batch experiments in support of process development objectives.
• Prepare media, inoculum, and feed solutions for fermentation runs.
• Set up, sterilize, calibrate, and maintain fermentation reactors.
• Perform routine analytical work, including OD measurements and metabolite analysis.
• Contribute to safe, rigorous laboratory operations.
• Collaborate closely with strain engineering, downstream, and analytical teams to support integrated process development as the platform scales.

Skills

Microbial fermentation

Bench-scale bioreactors

Aseptic technique

Experimental troubleshooting

Tools

HPLC

Job description

Flagship Pioneering in Cambridge, MA is seeking a Research Associate I/II to support the development and optimization of microbial fermentation processes for recombinant protein production. The role is hands-on and involves building a fermentation platform within a fast-paced startup setting.

You will operate shake flasks and bench-scale bioreactors, prepare media, monitor runs, and collaborate with strain engineering, downstream, and analytical teams to drive scalable process development and