Biophysics Research Scientist: Cryopreservation

University of Minnesota; Minneapolis (MN); On-site; USD 73,000 - 80,000; Full time

Benefits offered by this job

Competitive wages & benefits

Tuition benefits

Diversity & inclusion programs

Job summary

The University of Minnesota invites applications for a one-year, full-time position in the Mechanical Engineering department, conducting membrane permeabilization experiments and associated SOP development. The role is in-person at UMN - TC, East Bank and includes leadership of protocol execution and data reporting.

The ideal candidate has strong cell culture, SOP-building, and cross-site collaboration skills, with a track record of thorough documentation and communication with the PI and

Qualifications

• BA/BS in biomedical engineering, biology, biochemistry, chemistry, materials science, pharmaceutical formulation development or a related field plus at least five years of relevant experience or a combination of education and relevant work experience to equal at least nine years.
• Hands-on experience with mammalian cell culture, and cell-viability assessment techniques.
• Ability to follow, write, and maintain detailed SOPs and laboratory records.
• Strong organizational skills and reliability in meeting a structured schedule of deliverables.
• Clear written and verbal communication skills for cross-site collaboration and reporting.

Responsibilities

• Lead experiments and adopt reversible membrane permeabilization technology.
• Completing training to master protocols for reversible membrane permeabilization.
• Perform installation, calibration, characterization, and validation of membrane permeabilization systems.
• Establish parameters to ensure consistent, high-efficiency intracellular delivery of cryoprotectant agents; troubleshoot as needed.
• Prepare SOPs and coordinate with other collaborating sites to ensure uniformity of results.
• Train other lab staff in the adopted technology.
• Conduct physicochemical characterization & cryopreservation experiments using DSC and FTIR SOPs.
• Characterize the physical states, glass transition behaviors, and aging characteristics of cryoprotectant cocktails.
• Develop freeze/thaw protocols for different cryoprotectant cocktails and prepare SOPs while coordinating adoption.
• Perform post-thaw viability analyses and report results to PI and collaborators.

Skills

Cell culture experience

SOP development

Lab coordination

Written and verbal communication

Education

BA/BS in biomedical engineering or related field

Tools

None

Job description

The University of Minnesota invites applications for a one-year, full-time position in the Mechanical Engineering department, conducting membrane permeabilization experiments and associated SOP development. The role is in-person at UMN - TC, East Bank and includes leadership of protocol execution and data reporting.

The ideal candidate has strong cell culture, SOP-building, and cross-site collaboration skills, with a track record of thorough documentation and communication with the PI and