Biomolecular Characterization Scientist II – Antibody Binding & HTS

BigHat Biosciences; San Mateo (CA); On-site; USD 145,000 - 165,000; Full time

Benefits offered by this job

Bonus

Stock options

Benefits

Job summary

BigHat Biosciences is seeking a Scientist II or Senior Scientist I in Biomolecular Characterization to drive antibody–target binding characterization, develop new assay capabilities, and represent the team across BigHat’s programs.

Key responsibilities include designing and implementing binding strategies using BLI and SPR, collaborating with discovery and lead optimization teams, and communicating results to decision-makers to accelerate program progression.

Qualifications

• Ph.D. with 2–5 years, or MSc with 5+ years of independent industry research in binding assays.
• Fluency in bioanalytical science, biochemistry, biophysics, and assay design.
• Experience with lab automation and working with automation engineers.

Responsibilities

• Develop, optimize, and implement high- and low-throughput strategies to characterize antibody–antigen interactions.
• Implement best practices for binding assay design across formats.
• Troubleshoot assay issues and interpret antibody–antigen data for stakeholders.

Skills

High-throughput assays

BLI/SPR data analysis

Cross-functional collaboration

Education

PhD

MSc

Tools

BLI

SPR

ELISA/MSD

Flow Cytometry

Carterra

Cytiva

Sartorius

Job description

BigHat Biosciences is seeking a Scientist II or Senior Scientist I in Biomolecular Characterization to drive antibody–target binding characterization, develop new assay capabilities, and represent the team across BigHat’s programs.

Key responsibilities include designing and implementing binding strategies using BLI and SPR, collaborating with discovery and lead optimization teams, and communicating results to decision-makers to accelerate program progression.