Biometrics VP & Data Strategy Leader

Climb Bio; Wellesley (MA); Hybrid; USD 305,000 - 410,000; Full time

Benefits offered by this job

Discretionary annual bonus

Comprehensive benefits (Medical,Dental

Vision

Life & Disability insurance

401k company match

Employee Stock Purchase Program

Generous paid time off

Equity

Job summary

Climb Bio is seeking an experienced Vice President, Head of Biometrics to lead all biometrics activities across our clinical development programs in a lean biotech environment. This hands-on role oversees Biostatistics, Statistical Programming, and Data Management, mentoring a small team and partnering with Clinical Development leadership to ensure data quality and regulatory readiness.

The position requires a strong track record in biostatistics, leadership, and collaboration, with extensive

Qualifications

• MS or PhD in Biostatistics, Statistics, or a related quantitative discipline.
• 12+ years of experience in the biotechnology or pharmaceutical industry, including substantial experience as a practicing biostatistician.
• Demonstrated progression into biometrics leadership with responsibility for biostatistics and broader biometrics functions.
• Experience overseeing Statistical Programming and Data Management activities.
• Proven success managing outsourced biometrics models and CRO partnerships.
• Experience supporting clinical studies through regulatory submissions and health authority interactions.
• Strong understanding of clinical trial design, CDISC standards, and clinical data workflows.
• Ability to operate both strategically and hands-on in a resource-conscient environment.
• Excellent communication, collaboration, and leadership skills.

Responsibilities

• Lead the biometrics strategy across all clinical development programs.
• Serve as the lead statistician and biometrics representative on study teams.
• Provide statistical leadership for study design, endpoints, protocol development, sample size determination, and statistical analysis plans.
• Oversee all biometrics activities, including biostatistics, statistical programming, and data management.
• Manage and mentor a small team of internal and outsourced biometrics professionals.
• Provide oversight of CROs and external vendors to ensure high-quality, timely, and cost-effective execution.
• Review and interpret clinical data analyses and communicate findings to study teams and executive leadership.
• Support regulatory submissions and interactions with health authorities, including preparation and review of biometrics deliverables.
• Establish and maintain appropriate biometrics processes, standards, and quality practices.
• Partner closely with Clinical Operations, Medical Affairs, Regulatory Affairs, Pharmacovigilance, and external vendors to ensure successful program execution.

Skills

Biostatistics

Leadership

Communication

Collaboration

Project management

Education

MS/PhD in Biostatistics

Tools

CDISC standards

Statistical Programming

Data Management

Job description

Climb Bio is seeking an experienced Vice President, Head of Biometrics to lead all biometrics activities across our clinical development programs in a lean biotech environment. This hands-on role oversees Biostatistics, Statistical Programming, and Data Management, mentoring a small team and partnering with Clinical Development leadership to ensure data quality and regulatory readiness.

The position requires a strong track record in biostatistics, leadership, and collaboration, with extensive