Biologics DP Development Scientist II – HPLC SME

SmartRecruiters, Inc.; South San Francisco (CA); On-site; USD 85,000 - 162,000; Full time

Job summary

AbbVie in South San Francisco, CA, is seeking a Scientist II to lead biologics drug product development, focusing on formulation, process and in-use studies. You will drive HPLC/UPLC strategies, ensure instrument uptime, and collaborate across analytical development and drug substance teams.

The role requires a strong background in biologics formulation/characterization, independence to manage multiple projects, and excellent communication. Onsite lab-based position.

Qualifications

• Hands-on experience in biologics drug product development, including formulation and characterization.
• Strong understanding of protein degradation pathways and analytical approaches for product quality.
• Experience with HPLC/UPLC across multiple modalities and troubleshooting.
• Proficiency in data analysis and scientific reporting for regulatory purposes.

Responsibilities

• Lead formulation and biologics drug product development studies for clinical programs.
• Generate robust data and documentation for IND/NDA/BLA submissions and CTD modules.
• Collaborate with Analytical Development and Drug Substance teams to advance programs.
• Serve as HPLC/UPLC SME and maintain instruments; lead troubleshooting and maintenance.

Skills

HPLC/UPLC expertise

Analytical chemistry

Data analysis

Technical communication

Education

Bachelor’s degree in Pharmaceutical Sciences, Chemistry, Biochemistry, Chemical Engineering, or related

4–5 years (Scientist I) or 7+ years (Scientist II) of relevant industry experience

Tools

Empower software

Job description

AbbVie in South San Francisco, CA, is seeking a Scientist II to lead biologics drug product development, focusing on formulation, process and in-use studies. You will drive HPLC/UPLC strategies, ensure instrument uptime, and collaborate across analytical development and drug substance teams.

The role requires a strong background in biologics formulation/characterization, independence to manage multiple projects, and excellent communication. Onsite lab-based position.