Bioinformatics Research Assistant - Pediatrics Newborn Medicine

Washington University in St. Louis; St. Louis (MO); On-site; USD 36,000 - 61,000; Full time

Job summary

Washington University in St. Louis seeks a Bioinformatics Research Assistant to join a collaborative team uncovering the genomic basis of rare diseases.

The role involves analyzing large whole genome and exome sequencing data, RNA sequencing, and epigenomics data to support variant discovery and prioritization. You will run computational pipelines on a local HPC cluster, manage and transfer large datasets, and help evaluate new methods while collaborating with geneticists, bioinformaticians, and

Qualifications

• Bachelor’s degree or combination of education and/or experience may substitute for minimum education.
• No specific certification/professional license is required for this position.
• No specific work experience is required for this position.
• A driver's license is not required for this position.

Responsibilities

• Run computational bioinformatics pipelines on a local high-performance computing cluster to analyze genomic datasets.
• Conduct variant analysis and curation, helping to identify genomic variants underlying rare disease.
• Maintain and manage large datasets, including data storage and data transfer of genomic data.
• Contribute to developing and refining computational workflows to improve the efficiency and accuracy of genomic data processing and analysis.
• Work closely with a multidisciplinary team of geneticists, bioinformaticians, and clinicians to communicate findings and interpret results within the context of rare disease research.
• Assist in preparing project reports, presentations, and manuscripts as needed.
• Performs other duties as assigned.

Job description

Location ST. LOUIS, MO 63108 Scheduled Hours 40 Position Summary This Bioinformatics Research Assistant is a dry-lab position and will play a key role in a collaborative team dedicated to uncovering the genomic basis of rare diseases as part of the Washington University Undiagnosed Diseases Network and other WashU local rare disease projects. This role focuses on working with large genomic datasets to analyze data from whole genome and exome sequencing, short- and long-read RNA sequencing, long-read genome sequencing, and epigenomics data. This technician will support the execution of bioinformatics workflows and pipelines to facilitate variant discovery, perform variant analysis/prioritization based on biological relevance, manage storage and transfer of large datasets, and assist in evaluating new computational methods and tools.

Job Description

Primary Duties & Responsibilities:

• Run computational bioinformatics pipelines on a local high-performance computing cluster to analyze genomic datasets.
• Conduct variant analysis and curation, helping to identify genomic variants underlying rare disease.
• Maintain and manage large datasets, including data storage and data transfer of genomic data.
• Contribute to developing and refining computational workflows to improve the efficiency and accuracy of genomic data processing and analysis.
• Work closely with a multidisciplinary team of geneticists, bioinformaticians, and clinicians to communicate findings and interpret results within the context of rare disease research.
• Assist in preparing project reports, presentations, and manuscripts as needed.
• Performs other duties as assigned.

Working Conditions

Job Location/Working Conditions Works in a laboratory environment with potential exposure to biological and chemical hazards Must be physically able to wear protective equipment and to provide standard care to research animals Normal office environment Physical Effort Typically sitting at desk or table Repetitive wrist, hand or finger movement Equipment Office equipment

The above statements are intended to describe the general nature and level of work performed by people assigned to this classification.

They are not intended to be construed as an exhaustive list of all job duties performed by the personnel so classified.

Management reserves the right to revise or amend duties at any time.

Required Qualifications

Education: Bachelor’s degree or combination of education and/or experience may substitute for minimum education. Certifications/Professional Licenses: No specific certification/professional license is required for this position. Work Experience: No specific work experience is required for this position. Skills: Not Applicable Driver's License: A driver's license is not required for this position.

More About This Job

WashU seeks highly motivated individuals who are able to perform duties in a manner consistent with our core mission and guiding principles.

Preferred Qualifications

Education: Bachelor's degree - Bioinformatics, Bachelor's degree - Biology, Bachelor's degree - Computational Biology Certifications/Professional Licenses: No additional certification/professional licenses unless stated elsewhere in the job posting. Work Experience: Relevant Experience (1 Year) Skills: Analytical Thinking, Bash (Programming Language), Bioinformatics, Bioinformatics Tools, Biostatistics, Communication, Complex Data Analysis, Computational Biology, Computer Science, Critical Reasoning, Data Management, Data Reporting, Datasets, Exome Sequencing, Genome Sequencing, Genomics Research, Human Genetics, Linux, Microarrays, Model Organism, Problem Solving, Python (Programming Language), Rare Diseases, R Programming, Sequence Analysis Grade R07-H Salary Range $17.10 - $29.09 / Hourly The salary range reflects base salaries paid for positions in a given job grade across the University. Individual rates within the range will be determined by factors including one's qualifications and performance, equity with others in the department, market rates for positions within the same grade and department budget.

Questions

For frequently asked questions about the application process, please refer to our External Applicant FAQ. Q: Can I create a job alert to notify me when jobs of interest are posted? A: Yes! After you create a Candidate Home account, you can set up and manage job alerts to be sent to you either daily or weekly, according to the filters you select. You can add, edit, or delete job alerts at any time. You will need to opt in to communications from WashU when you set up your first alert and will only receive alerts for jobs posted after the alert has been created. Set alerts today so you do not miss any new opportunities! Washington University in St. Louis' collective success is significantly attributed to the passion and outstanding efforts of our community. Our staff, faculty and trainees are committed to excellence and dedicated to carrying out our missions of research, teaching and patient care. WashU prides itself on being a place where people matter, and serious work is done. Our people work together in an inclusive community that celebrates diverse perspectives, collaboration and innovation. We are a community of individuals inspired to work together to develop big ideas and tackle challenging problems. We value the well-being of our people. WashU strives to create a positive employee experience where staff, faculty and trainees thrive, both personally and professionally. Our employees find meaning, connection and vitality in their work and life with healthy work-life balance and support to learn, grow and make an impact at WashU, the community and the world.

Accommodation

If you are unable to use our online application system and would like an accommodation, please email [e-mail] or call the dedicated accommodation inquiry number at 314-935-1149 and leave a voicemail with the nature of your request.

All qualified individuals must be able to perform the essential functions of the position satisfactorily and, if requested, reasonable accommodations will be made to enable employees with disabilities to perform the essential functions of their job, absent undue hardship.

Pre-Employment Screening

All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. The screenings will include criminal background check and, as applicable for the position, other background checks, drug screen, an employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.

Benefits Statement

• Personal Up to 22 days of vacation, 10 recognized holidays, and sick time.
• Competitive health insurance packages with priority appointments and lower copays/coinsurance.
• Take advantage of our free Metro transit U-Pass for eligible employees.
• WashU provides eligible employees with a defined contribution (403(b)) Retirement Savings Plan, which combines employee contributions and university contributions starting at 7%.
• Wellness Wellness challenges, annual health screenings, mental health resources, mindfulness programs and courses, employee assistance program (EAP), financial resources, access to dietitians, and more!
• Family We offer 4 weeks of caregiver leave to bond with your new child.
• Family care resources are also available for your continued childcare needs.
• Need adult care? We’ve got you covered.
• WashU covers the cost of tuition for you and your family, including dependent undergraduate-level college tuition up to 100% at WashU and 40% elsewhere after seven years with us.
• For policies, detailed benefits, and eligibility, please visit: https://hr.wustl.edu/benefits/

EEO Statement

Washington University in St. Louis is committed to the principles and practices of equal employment opportunity. It is the University’s policy to provide equal opportunity and access to persons in all job titles without regard to race, ethnicity or shared ancestry, color, national origin, citizenship (where prohibited by federal law), age, religion, sex, sexual orientation, gender identity or expression, disability, protected veteran status, or genetic information. As a federal contractor, the university maintains affirmative action programs to implement its equal employment opportunity policy for individuals with disabilities and protected veterans, in accordance with Section 503 of the Rehabilitation Act of 1973, as amended, and the Vietnam Era Veterans’ Readjustment Assistance Act of 1974 (VEVRAA), as amended.

Useful Links

Who We Are Human Resources Benefits Living in St. Louis Frequently Asked Questions Accommodation If you are unable to use our online application system and would like an accommodation, please email [e-mail] or call the dedicated accommodation inquiry number at 314-935-1149 and leave a voicemail with