Bioinformatician I — Neurology Data Pipelines

Mount Sinai Health System; New York (NY); On-site; USD 65,000 - 91,000; Full time

Job summary

The Mount Sinai Health System seeks a Bioinformatician to implement, validate, optimize, and maintain robust bioinformatics workflows in Linux-based environments. The role emphasizes software development skills and hands-on pipeline work with attention to quality and regulatory standards.

Responsibilities include designing and validating NGS pipelines, SV&V protocols, documentation, and collaboration with wet-lab, QA, clinical operations, and product management to meet timelines and business

Qualifications

• 3 years' experience required; 2+ years of software development in Linux environment preferred.
• Programming experience in Python, R, or Bash highly preferred.
• Solid understanding of NGS technologies and analytical methods.

Responsibilities

• Implement NGS bioinformatics pipelines, including annotation, QC, and downstream analysis.
• Own end-to-end validation of pipelines to meet scientific and regulatory standards.
• Execute SV&V protocols and maintain thorough documentation of results.
• Evaluate new tools and software for integration into workflows.
• Troubleshoot pipeline failures and perform root-cause analyses.
• Ensure reproducibility, scalability, and robustness of workflows.
• Collaborate with wet-lab, QA, clinical ops, and product management to align objectives with timelines.
• Maintain records of implementation, validation activities, version control, and release notes.
• Prepare documentation for internal quality audits.

Skills

Python

R

Bash

NGS workflows

Education

Bachelor's degree in Biological Sciences or related

Master's degree preferred

Tools

Nextflow

Snakemake

WDL/Cromwell

Linux

Job description

The Mount Sinai Health System seeks a Bioinformatician to implement, validate, optimize, and maintain robust bioinformatics workflows in Linux-based environments. The role emphasizes software development skills and hands-on pipeline work with attention to quality and regulatory standards.

Responsibilities include designing and validating NGS pipelines, SV&V protocols, documentation, and collaboration with wet-lab, QA, clinical operations, and product management to meet timelines and business