Bioinformatician I Channing Lab

Brigham and Women's Hospital; Boston (MA); On-site; USD 80,000 - 110,000; Full time

Job summary

Join a forward-thinking institution dedicated to advancing medical research through bioinformatics. In this exciting role, you'll work on complex data management challenges involving genomic-scale next-generation sequencing data. Collaborate with a talented team to design and support analysis pipelines while utilizing cutting-edge machine learning tools. This position offers a unique opportunity to contribute to groundbreaking projects that will shape the future of healthcare. If you're passionate about data and its potential to drive innovation in medicine, this is the perfect opportunity for you.

Qualifications

• MS in Bioinformatics, Computer Science, or Biological Engineering required.
• Experience in programming with agile development methods is essential.

Responsibilities

• Develop and support infrastructure for data collection and analysis.
• Design and create software analysis pipelines for complex datasets.

Skills

Statistical and machine learning techniques

R programming

Python (Pandas)

Bioinformatics tools (BWA, samtools, GATK)

OMICs data types knowledge

PostgreSQL and database design

ETL procedures

Docker

Kubernetes

Linux (Ubuntu)

Education

MS in Bioinformatics

MS in Computer Science

MS in Biological Engineering

Tools

Docker

Kubernetes

Snakemake

Nextflow

PostgreSQL

Job description

Job Overview

The Channing Division of Network Medicine at Brigham and Women's Hospital, Boston, is seeking exceptional candidates to join the Bioinformatics Core. The core handles a wide variety of data management challenges involving complex datasets, including genomic-scale next-generation sequencing data, data processing, and curation. Our projects involve analyzing genome, transcriptome, and epigenome data using machine learning tools and data analysis pipelines.

The Bioinformatics team will develop and support the complex infrastructure necessary for data collection, transformation, and analysis, integrating various skills and techniques. Responsibilities include designing, creating, supporting tools and software analysis pipelines, and ensuring secure dissemination of generated information.

Qualifications

MS in Bioinformatics, Computer Science, or Biological Engineering. Candidates should have experience programming with agile development methods.

Skills, Abilities, and Competencies

• Ability to apply statistical and machine learning techniques to solve 'big data' problems
• Proficiency in programming with R, Python (Pandas)
• Understanding of bioinformatics tools, including common NGS tools such as BWA, samtools, GATK
• Knowledge of OMICs data types like DNA, RNA, methylation, 16S, and metabolomics
• Experience with databases (PostgreSQL) and database design
• Experience with ETL procedures
• Familiarity with Docker, Kubernetes, Snakemake, or Nextflow
• Ability to work independently in a highly collaborative and intellectually challenging environment
• Knowledge of Linux (Ubuntu)
• Excellent oral and written communication skills

Additional Information

Brigham and Women's Hospital is an Equal Opportunity Employer. We value diverse skills, perspectives, and ideas. All qualified applicants will receive consideration without regard to race, color, religion, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, or other protected status. We provide reasonable accommodations for individuals with disabilities during the application and interview process.