Bioinformatician

Natera; United States; Remote; USD 101,000 - 128,000; Full time

Job summary

Natera is seeking a Bioinformatician to join its innovative team in developing genomics analysis tools that enhance understanding of the immune response to cancer. The ideal candidate will possess strong expertise in bioinformatics, immunology, and data analysis, playing a pivotal role in transforming clinical datasets into actionable insights as part of advancing cancer treatment.

Benefits

Comprehensive medical, dental, vision, life and disability plans

401k benefits

Employee referral program

Free testing for employees and families

Fertility care benefits

Qualifications

• Great understanding of immunology and human genetics.
• Experience analyzing genomic sequencing data.
• Strong programming skills in bioinformatics scripting languages.

Responsibilities

• Develop computational tools for predicting antigenic somatic variants.
• Analyze T-cell receptor binding data.
• Run and enhance pipelines for NGS analysis.

Skills

Immunology

Bioinformatics

Genomics

Data Analysis

Programming in Python

SQL

Project Management

Education

PhD in Bioinformatics

MS in a related field with 3+ years experience

Tools

UNIX shell

Illumina platforms

RNA-seq

Job description

Join to apply for the Bioinformatician role at Natera

Join to apply for the Bioinformatician role at Natera

Title: Bioinformatician

Position Summary: We are seeking a bioinformatician with immunology experience to join a multidisciplinary team developing leading-edge genomics analysis tools to understand the immune system's response to cancer. This self-motivated, detail-oriented individual would join the Therapeutics and Innovations group and will be responsible for developing and applying bioinformatics methods to immuno-oncology clinical datasets, creating descriptive summary statistics and data visualizations, and technical reports.

Primary Responsibilities

• With the assistance of a multidisciplinary team, develop or enhance computational tools to predict antigenic somatic variants
• Assist bioinformaticians and data scientists in developing approaches to gain better understanding of T-cell receptor binding to MHC-peptide complexes.
• Use internal and external genomics data sources to understand how somatic and germline variation impacts the immune system’s response to cancer
• Run and enhance established immune repertoire sequencing pipelines and workflows for NGS analysis in a clinical setting
• Prototype, develop, document, deploy, and support novel clinical DNA and RNA sequencing analysis approaches NGS analysis
• Benchmark new tools for sequencing data analysis and propose improvements
• Develop QC metrics, gold standard datasets and tools for systematically testing and evaluating the accuracy of newly developed assays and methods
• Collaborate with technical teams in specifying requirements for tools to enhance workflow efficiency, turnaround times and robustness
• Participate in internal research projects and external research collaborations
• Assist in preparing text and figures for manuscripts and external presentations
• Summarize results in written or oral reports for computational biologists, molecular biologists, clinicians, and internal researchers
  
  

Required Skills / Experience

• Great understanding of immunology and human genetics (understanding of oncology is preferred).
• Experience analyzing genomic sequencing data from Illumina platforms
• Experience analyzing long-read nucleic acid datasets such as PacBio or Oxford Nanopore
• Experience analyzing high-throughput RNA-seq data
• Familiarity with using and scripting in UNIX shell (e.g. Bash)
• Strong programming skills in common bioinformatics scripting languages (e.g. Python, R)
• Ability to collaborate and communicate with other scientists, researchers and clinicians
• Demonstrated project management skills and ability to produce readable, reproducible and documented code (e.g. Jupyter, R markdown, etc)
• Strong team-oriented work ethic with open, honest, and considerate communication skills
• Immune repertoire analysis experience is a plus(e.g. Immcantation, MiXCR, TRUST4, immunarch, etc)
• Experience writing SQL queries for data retrieval is required is a plus
• Exposure to cancer genomics somatic variant calling is a plus
• Experience working with large external data sources such as IEDB, iReceptor, VDJdb, and others is a plus
  
  

Education /Experience

• PhD degree in bioinformatics, computational biology, statistics, immunology, or a related field; or MS degree with 3+ years of post-graduation experience in bioinformatics, biology, computational biology, statistics, immunology, or a related field.
  
  

The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations.

Remote USA

$101,800—$127,300 USD

OUR OPPORTUNITY

Natera is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.

The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.

What We Offer

Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!

For more information, visit www.natera.com.

Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.

All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.

If you are based in California, we encourage you to read this important information for California residents.

Link: https://www.natera.com/notice-of-data-collection-california-residents/

Please be advised that Natera will reach out to candidates with a @natera.com email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes.

For More Information

• BBB announcement on job scams
• FBI Cyber Crime resource page
  
  

Seniority level

• Seniority level

  Mid-Senior level

Employment type

• Employment type

  Full-time

Job function

• Job function

  Research, Analyst, and Information Technology

• Industries

  Biotechnology Research, Pharmaceutical Manufacturing, and Software Development

Referrals increase your chances of interviewing at Natera by 2x

Get notified about new Bioinformatician jobs in United States.

United States $130,000.00-$150,000.00 1 day ago

San Jose, CA $63,450.00-$104,235.00 1 week ago

San Jose, CA $81,120.00-$133,260.00 1 week ago

Business Data Analyst - Remote Nationwide

Eden Prairie, MN $71,600.00-$140,600.00 1 day ago

Data Management Analyst, Junior (Future Need)

Arlington, VA $30,000.00-$40,000.00 3 weeks ago

Master Data Analyst (SAP, Excel) - 100% Remote

Business Data Analyst - Remote Nationwide

United States $71,600.00-$140,600.00 1 day ago

Irvine, CA $90,000.00-$120,000.00 3 weeks ago

United States $90,000.00-$100,000.00 15 hours ago

United States $100,000.00-$140,000.00 1 day ago

Data Reporting Business Analyst (Remote - US)

United States $80,000.00-$95,000.00 16 hours ago

Business Operations Data Analyst - Remote

Senior Data Analyst, Growth and Lifecycle Marketing

Senior Workforce Management Data Analyst

United States $136,400.00-$178,300.00 1 week ago

New York, United States $55,000.00-$65,000.00 3 days ago

Palo Alto, CA $150,000.00-$200,000.00 14 hours ago

We’re unlocking community knowledge in a new way. Experts add insights directly into each article, started with the help of AI.