Bioelectronics Research Engineer

Protocol Labs, Inc.

Pasadena (TX)

On-site

USD 70,000 - 100,000

Full time

14 days+

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Job summary

Melody is an early-stage research organization based in Pasadena, engineering continuous molecular monitoring technology and closed-loop interventions for human health. We are hiring a Research Associate to join the scientific team and build Melody's bioelectronics foundry.

You will evolve and test protein biosensors, moving candidates from DNA constructs to purified proteins and device-ready assays. You will work across molecular biology, liquid handling robotics, and novel hardware,

Qualifications

BA or BS in biology, chemistry, physics or other relevant field.
2+ years of wet-lab bench experience with protein engineering or biophysical assays.
Demonstrated precision in experimental work and project management.

Responsibilities

Express and purify engineered binders and biosensors.
Design, order, and prepare DNA constructs, mutant libraries, and binder-reporter variants.
Run fluorescence, plate-reader, biochemical, biophysical, and device-based assays.
Generate dose-response curves and quantify EC50/Kd, dynamic range, signal-to-noise, selectivity, kinetics, reversibility, stability, and drift.
Support yeast display, FACS-based screening, and directed evolution workflows.
Interface biosensors with optical and electrochemical readouts on benchtop hardware.
Help automate assay workflows using liquid handlers, plate readers, and custom scripts.
Maintain clean records of constructs, samples, sequence-function relationships, assay metadata, instrument settings, and experimental results.
Collaborate with scientists and engineers to turn one-off assays into repeatable workflows that scale to the needs of the platform.