Bioconjugation Scientist (ADC Linker Chemistry)

PerkinElmer; South San Francisco (CA); On-site; USD 76,000 - 102,000; Full time

Job summary

PerkinElmer in South San Francisco, CA seeks a chemist to contribute to Discovery Chemistry, applying conjugation, purification, and analytical strategies to advance drug candidates. You will work on bioconjugates and biologics, interpret LC/MS data, and document findings for multidisciplinary teams.

The role requires a solid organic chemistry background, 2+ years of related experience, and the ability to learn quickly in a collaborative environment within a fast-paced lab.

Qualifications

• B.S. in chemistry, biochemistry, or related field with 2+ years of experience.
• Hands-on bioconjugation, purification, and characterization of ADCs (preferred).
• Strong organic chemistry foundation and lab synthesis experience.
• Ability to learn quickly and work in cross-disciplinary teams.

Responsibilities

• Perform bioconjugations of linker-payloads to antibodies using established methods.
• Purify biologics using SEC, hydrophobic interaction, and ion-exchange chromatography.
• Acquire and interpret LC/MS and other analytical data.
• Document results and present data to project teams.

Skills

Bioconjugation

Analytical techniques

Team collaboration

Reaction setup & optimization

Education

B.S. in Chemistry or Biochemistry

Tools

HIC

SEC

RP chromatography

SDS-PAGE

UV-Vis

Job description

PerkinElmer in South San Francisco, CA seeks a chemist to contribute to Discovery Chemistry, applying conjugation, purification, and analytical strategies to advance drug candidates. You will work on bioconjugates and biologics, interpret LC/MS data, and document findings for multidisciplinary teams.

The role requires a solid organic chemistry background, 2+ years of related experience, and the ability to learn quickly in a collaborative environment within a fast-paced lab.