Bioassay Development Senior Scientist

BioSpace; Framingham (MA); On-site; USD 120,000 - 180,000; Full time

Job summary

Sanofi in Framingham, MA is seeking a Bioassay Development Senior Scientist with strong cell and molecular biology expertise to advance analytical methods for early and late-stage programs. You will join a multidisciplinary Bioassay Development group and lead experiments, mentor junior staff, and drive project timelines in a fast-paced environment.

The successful candidate will have a PhD or MSc with extensive experience in mammalian systems, potency assays, and collaboration across biologists,

Qualifications

• PhD or MSc with relevant research experience as stated.
• Experience with mammalian cell culture and cell line engineering or transgenic models.
• Experience with at least two of the following techniques: qPCR, Western blot, plate-based assays (ELISA, fluorescence).

Responsibilities

• Initiate, design, and execute analytical experiments to develop and qualify relative potency methods for clinical molecules.
• Engineer novel cell lines to evaluate mechanism of action.
• Support mAb and bi/tri-specific development and other modalities.
• Maintain good documentation with electronic lab notebook.
• Ensure GMP compliance and draft SOPs as needed.
• Collaborate across interdisciplinary teams including biology, chemistry, quality and legal.
• Lead and contribute to presentations and publications; communicate findings clearly.
• Mentor interns and junior scientists; foster a collaborative environment.
• Collaborate with CROs/CDMOs for training and testing activities.

Skills

Mammalian cell culture

qPCR

Western blotting

ELISA/plate-based assays

Scientific communication

Time management

Mentoring interns

Education

PhD in Molecular Biology / Cell Biology / Biochemistry / Biotechnology / Immunology / Microbiology / Biomedical Sciences or related

Masters in one of the above or related fields with 4+ years of experience

Tools

SnapGene

SoftMax

Luminometer

Job description

Job Title: Bioassay Development Senior Scientist

• Location: Framingham, MA

About The Job

Sanofi is committed to being a world-class biologics research organization, striving to bring next generation, transformative therapies to patients. Our BioAnalytics US team, as part of Global CMC Development organization, plays a critical role in advancing Sanofi's R&D pipelines from early discovery through late-stage development.

We are seeking a talented and highly motivated Senior Scientist with expertise in Cell and Molecular Biology to join the Bioassay Development group in Framingham, MA. In this role, you will be a key contributor to a multidisciplinary team, driving analytical method development, optimization and routine testing to support R&D programs to meet project goals within established timelines.

This position offers meaningful growth opportunities from expanding technical expertise and assuming increasing project leadership responsibilities, to charting a pathway toward senior scientific or leadership roles within Analytical Development and the broader BioAnalytics organization.

Join the engine of Sanofis mission where deep immunoscience meets bold, AI-powered research. In R&D, youll drive breakthroughs that could turn the impossible into possible for millions.

About Sanofi

We're an R&D-driven, AI-powered biopharma company committed to improving peoples lives and delivering compelling growth. Our deep understanding of the immune system and innovative pipeline enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve peoples lives.

Main Responsibilities

• Apply scientific expertise and judgement to initiate, design, direct and execute analytical experiments to develop and qualify relative potency methods for early and late-stage clinical molecules.
• Innovate and engineer novel cell lines with which to evaluate molecules mechanisms of action.
• Support mAb and bi/tri-specific development as well as other modalities such as viral and non-viral gene therapy.
• Maintain good documentation practices using the electronic lab notebook system.
• Maintain GMP compliance by following GMP procedures in the laboratory, by supporting routine maintenance activities in the department, and by training on drafting appropriate SOPs.
• Collaborate closely with interdisciplinary and cross-functional teams, including biologists, chemists, quality, legal and other stakeholders.
• Lead and contribute to high-profile presentations and publications, ensuring effective communication of research findings and methodologies.
• Support the growth of the team by mentoring interns and junior scientists, sharing knowledge and fostering a collaborative research environment.
• Collaborate with CROs and CDMOs for training, outsourced activities, co-validation or testing.

About You

Basic Qualifications

• PhD in Molecular Biology, Cell Biology, Biochemistry, Biotechnology, Immunology, Microbiology, Biomedical Sciences, Life Sciences or a related field with a with a minimum of 1 year of relevant research experience. Academic research, thesis work, co-ops, and/or internships will be considered.
• OR a Masters degree in one of the above or related fields with at least 4 years of relevant experience. Academic research experience will be considered.
• Experience in mammalian cell culture and either engineering cell lines or transgenic model systems.
• Extensive experience in at least two of the following cell and molecular biology techniques: qPCR, Western blotting, and plate-based assays (e.g., ELISA, fluorescence-based assays).
• Strong time management skills to execute in a dynamic, fast-paced environment.
• Excellent organization and scientific communication skills.

Preferred Qualifications

• Experience with SnapGene, Softmax, luminometer or relative potency statistical analyses
• Knowledge of a biologics standard analytical methods and controls

Why Choose Us?

• Make your work count by supporting a company that brings life-changing treatments to millions and is committed to doing right by patients, communities, and the planet.
• Drive progress from within by helping simplify, scale, and modernize how a global biopharma business delivers smarter, faster, and more sustainably.
• Support teams across science, medicine, and operations by building better systems, shaping bold strategies, and enabling innovation at speed.
• Make an impact across borders and functions, collaborating with leaders to turn complex challenges into real-world solutions.
• Advance your career through stretch roles, cross-functional moves, and development opportunities designed to match your ambition.
• Thrive in inclusive, high-performing teams where every role matters and every voice helps shape whats next.

Sanofi US Services and its U.S. affiliates are Equal Opportunity employers committed to a culturally inclusive workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.