Bioassay Development Senior Scientist

Biopharma Careers; Framingham (MA); On-site; USD 101,000 - 145,000; Full time

Job summary

Sanofi US in Framingham, MA seeks a Bioassay Development Senior Scientist to lead analytical method development and qualification for early- to late-stage biologics. You will design experiments, mentor researchers, and collaborate across functions to advance R&D programs while maintaining GMP-compliant documentation.

The role requires a PhD with 1 year of experience or a Master’s with 4+ years, strong mammalian cell culture and cell line engineering skills, and experience with qPCR, Western

Qualifications

• PhD in Molecular Biology, Cell Biology, Biochemistry, Biotechnology, Immunology, Microbiology, Biomedical Sciences or related field with a minimum of 1 year of relevant research experience.
• OR a Master’s degree with at least 4 years of relevant experience; academic research considered.

Responsibilities

• Design, direct and execute analytical experiments to develop and qualify relative potency methods for early and late-stage clinical molecules.
• Engineer novel cell lines to evaluate mechanisms of action.
• Support mAb and bi-/tri-specific development and other modalities.
• Maintain good documentation using electronic lab notebook.
• Support GMP-compliant procedures and SOP drafting; ensure training when needed.
• Collaborate with cross-functional teams including biology, chemistry, quality and legal.

Skills

Mammalian culture

Cell line engineering

Transgenic models

qPCR

Western blot

ELISA

Time management

Scientific communication

Education

PhD in Molecular Biology/Cell Biology/Biochemistry/ Biotechnology/Immunology or related (1 year experience)

MS in above fields with 4+ years experience

Tools

SnapGene

SoftMax

Luminometer

Job description

Job Title: Bioassay Development Senior Scientist

Location: Framingham, MA

About the job

Sanofi is committed to being a world-class biologics research organization, striving to bring next generation, transformative therapies to patients. Our BioAnalytics US team, as part of Global CMC Development organization, plays a critical role in advancing Sanofi's R&D pipelines from early discovery through late-stage development. We are seeking a talented and highly motivated Senior Scientist with expertise in Cell and Molecular Biology to join the Bioassay Development group in Framingham, MA. In this role, you will be a key contributor to a multidisciplinary team, driving analytical method development, optimization and routine testing to support R&D programs to meet project goals within established timelines. This position offers meaningful growth opportunities, from expanding technical expertise and assuming increasing project leadership responsibilities, to charting a pathway toward senior scientific or leadership roles within Analytical Development and the broader BioAnalytics organization. Join the engine of Sanofi's mission, where deep immunoscience meets bold, AI-powered research. In R&D, you'll drive breakthroughs that could turn the impossible into possible for millions.

Main Responsibilities

• Apply scientific expertise and judgement to initiate, design, direct and execute analytical experiments to develop and qualify relative potency methods for early and late-stage clinical molecules.
• Innovate and engineer novel cell lines with which to evaluate molecules' mechanisms of action.
• Support mAb and bi/tri-specific development as well as other modalities such as viral and non-viral gene therapy.
• Maintain good documentation practices using the electronic lab notebook system.
• Maintain GMP compliance by following GMP procedures in the laboratory, by supporting routine maintenance activities in the department, and by training on drafting appropriate SOPs.
• Collaborate closely with interdisciplinary and cross-functional teams, including biologists, chemists, quality, legal and other stakeholders.
• Lead and contribute to high-profile presentations and publications, ensuring effective communication of research findings and methodologies.
• Support the growth of the team by mentoring interns and junior scientists, sharing knowledge and fostering a collaborative research environment.
• Collaborate with CROs and CDMOs for training, outsourced activities, co-validation or testing.

About you

Basic Qualifications

• PhD in Molecular Biology, Cell Biology, Biochemistry, Biotechnology, Immunology, Microbiology, Biomedical Sciences, Life Sciences or a related field with a with a minimum of 1 year of relevant research experience. Academic research, thesis work, co-ops, and/or internships will be considered.
• OR a Master's degree in one of the above or related fields with at least 4 years of relevant experience. Academic research experience will be considered.
• Experience in mammalian cell culture and either engineering cell lines or transgenic model systems.
• Extensive experience in at least two of the following cell and molecular biology techniques: qPCR, Western blotting, and plate-based assays (e.g., ELISA, fluorescence-based assays).
• Strong time management skills to execute in a dynamic, fast-paced environment.
• Excellent organization and scientific communication skills.

Preferred Qualifications

• Experience with SnapGene, Softmax, luminometer or relative potency statistical analyses
• Knowledge of a biologics' standard analytical methods and controls

Why Choose Us?

Make your work count by supporting a company that brings life-changing treatments to millions, and is committed to doing right by patients, communities, and the planet. Drive progress from within by helping simplify, scale, and modernize how a global biopharma business delivers smarter, faster, and more sustainably. Support teams across science, medicine, and operations by building better systems, shaping bold strategies, and enabling innovation at speed. Make an impact across borders and functions, collaborating with leaders to turn complex challenges into real-world solutions. Advance your career through stretch roles, cross-functional moves, and development opportunities designed to match your ambition. Thrive in inclusive, high-performing teams where every role matters and every voice helps shape what’s next.

Sanofi US Services and its U.S. affiliates are Equal Opportunity employers committed to a culturally inclusive workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

Sanofi US Services and its U.S. affiliates are Equal Opportunity employers committed to a culturally inclusive workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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Pursue progress , discover extraordinary Better is out there. Better medications, better outcomes, better science. But progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let’s be those people.

US and Puerto Rico Residents Only

North America Applicants Only

The salary range for this position is:

$100.500,00 - $145.166,66

All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.