Bioanalytical PK Scientist – LC-MS & LBA for Biologics

MSD; Upper Gwynedd Township (Montgomery County); On-site; USD 87,000 - 137,000; Full time

Benefits offered by this job

Medical

Dental

Vision

401(k)

Paid holidays

Vacation

Sick days

Job summary

Merck in the United States is seeking a bioanalytical scientist to execute quantitative methods for small molecules, peptides, and biologics using LC-MS and LBA platforms. You will deliver data for PK/PD and in vitro studies while supporting automated workflows and compliant lab operations.

The role requires a Bachelor’s with 3+ years (or MS with 1–2 years) in analytical chemistry or related field, with experience in LBA for large molecules and proficient LC-MS/MS.

Qualifications

• Bachelor’s degree with 3+ years relevant laboratory experience or MS degree (1-2 years relevant experience) in analytical chemistry, pharmaceutical sciences, pharmacology, biomedical, chemical engineering or related field.
• Experience with Ligand Binding Assays (LBA) quantitation of large molecules/biologics.
• Proficient in LC-MS/MS and LBA platforms; capable of hybrid LC-MS/LBA workflows.

Responsibilities

• Develop, validate, and execute quantitative bioanalytical methods using LC-MS/MS, LBA, and hybrid workflows.
• Generate, analyze, and deliver bioanalytical data for PK/PD and in vitro studies.
• Perform manual and automated sample preparation (e.g., protein precipitation, SPE, immunocapture).
• Maintain lab operations and ensure compliance with SOPs and regulatory guidelines.
• Support high-throughput workflows via robotics/automation.

Skills

LBA with biologics

LC-MS/MS

Teamwork

Communication

Data analysis

Small molecule analysis

Education

Bachelor’s degree with 3+ years lab experience

MS degree with 1-2 years experience

Tools

Microsoft Office

Job description

Merck in the United States is seeking a bioanalytical scientist to execute quantitative methods for small molecules, peptides, and biologics using LC-MS and LBA platforms. You will deliver data for PK/PD and in vitro studies while supporting automated workflows and compliant lab operations.

The role requires a Bachelor’s with 3+ years (or MS with 1–2 years) in analytical chemistry or related field, with experience in LBA for large molecules and proficient LC-MS/MS.