Associate Scientist / Scientist, Analytical Sciences (m/f/d)

ProtaGene, GmbH; Burlington, Northern (MA, KY); Hybrid; USD 90,000 - 120,000; Full time

Benefits offered by this job

Paid time off

Medical/dental/vision insurance

401(k)

Job summary

ProtaGene, GmbH in the United States seeks an Associate Scientist / Scientist in Analytical Sciences to perform physicochemical and biochemical characterization of biologics using HPLC/UPLC, IEF, CE, spectroscopy, and binding/kinetic assays. You will design experiments, analyze data, and communicate results while maintaining GLP-like records and collaborating across teams.

The role requires hands-on CRO/QC experience, strong software skills (Waters Empower), and an ability to manage multiple

Qualifications

• Master’s or bachelor’s degree in chemistry, Biochemistry, or a related scientific discipline with 2-5 years (MSc.) or 4-6 years (BSc.) of relevant industry experience.
• Demonstrated hands-on experience with analytical characterization techniques, particularly chromatography (U/HPLC), electrophoretic and isoelectric focusing (PA 800 Plus/Maurice), is required.
• Experience working in a CRO and/or GMP Quality Control (QC) environment is highly desirable.
• Proficiency with Waters Empower™ chromatography data software is a strong plus.
• Working knowledge of biotherapeutic analytical development (e.g., method qualification and/or validation and assay transfer).
• Experience with additional biophysical characterization techniques, such as SEC-MALS, DSC, circular dichroism (CD), FT-IR, or MFI, and/or LC-MS-based characterization of biotherapeutics is highly desirable but not required.
• Ability to independently plan and execute experiments while managing multiple priorities and maintaining timelines in a fast-paced environment.
• Ability to work successfully in both a team/matrix environment as well as independently.
• Experience with the analytical characterization of oligonucleotides a plus.

Responsibilities

• Perform physicochemical and biochemical characterization of biologics using techniques such as HPLC/UPLC, IEF, CE, spectroscopy, biochemical assays, and binding/kinetic assays.
• Independently design and execute laboratory studies, analyze data, troubleshoot, and communicate findings via reports, presentations, and team discussions.
• Prepare and maintain assay reagents, reference standards, controls, and materials for analytical testing activities.
• Maintain accurate laboratory records, ELNs, and protocols in line with company procedures and quality standards.
• Collaborate with multidisciplinary teams to ensure timely delivery of analytical results and project milestones.

Skills

HPLC/UPLC

IEF

Capillary electrophoresis

Spectroscopy

Biochemical assays

Binding/kinetic assays

Education

Bachelor's or Master's in Chemistry/Biochemistry

Tools

Waters Empower

Job description

Associate Scientist / Scientist, Analytical Sciences (m/f/d)

• Massachusetts , United States
• Operations

Your Responsibilities

Perform physicochemical and biochemical characterization of biologics using a variety of analytical techniques, including HPLC/UPLC, isoelectric focusing (IEF), capillary electrophoresis (CE), spectroscopic methods, biochemical assays, and binding/kinetic assays.

Independently design and execute laboratory studies, analyze and interpret data, troubleshoot analytical challenges, and communicate findings through technical reports, presentations, and team discussions.

Prepare and maintain assay reagents, reference standards, controls, and other materials required to support analytical testing activities.

Maintain accurate and compliant laboratory records, electronic laboratory notebooks (ELNs), experimental protocols, and supporting documentation in accordance with company procedures and quality standards.

Collaborate effectively with multidisciplinary teams to ensure the timely delivery of high-quality analytical results and project milestones.

Job requirements

Master’s or bachelor’s degree in chemistry, Biochemistry, or a related scientific discipline with 2-5 years (MSc.) or 4-6 years (BSc.) of relevant industry experience.

Demonstrated hands-on experience with analytical characterization techniques, particularly chromatography (U/HPLC), electrophoretic and isoelectric focusing (PA 800 Plus/Maurice), is required.

Experience working in a CRO and/or GMP Quality Control (QC) environment is highly desirable.

Proficiency with Waters Empower™ chromatography data software is a strong plus.

Working knowledge of biotherapeutic analytical development (e.g., method qualification and/or validation and assay transfer).

Experience with additional biophysical characterization techniques, such as SEC-MALS, DSC, circular dichroism (CD), FT-IR, or MFI, and/or LC-MS-based characterization of biotherapeutics is highly desirable but not required.

Ability to independently plan and execute experiments while managing multiple priorities and maintaining timelines in a fast-paced environment.

Ability to work successfully in both a team/matrix environment as well as independently.

Experience with the analytical characterization of oligonucleotides a plus.

What we offer

Benefits: Comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.

Work Environment: Laboratory-based position in a fast-paced, growth-oriented environment.

• Burlington , Massachusetts , United States