Associate Scientist – In Vivo Pharmacology, Oncology

Amgen; South San Francisco (CA); On-site; USD 110,000 - 170,000; Full time

Benefits offered by this job

Retirement and Savings Plan

Group medical, dental and vision

Stock-based incentives

Flexible work models

Job summary

Amgen is seeking an Associate Scientist in In Vivo Pharmacology, Oncology, to work onsite at the South San Francisco campus. You will generate and communicate in vivo data to support progression of oncology programs, collaborating across teams in a fast-paced environment.

The role involves hands-on mouse work, in vivo PK/PD studies, data analysis, and active participation in cross-departmental teams. A strong background in tumor biology and pharmacology is required.

Qualifications

• Requirements include advanced training in in-vivo rodent work and oncology-focused pharmacology.
• Experience with in-vivo cancer models and pharmacology is preferred.
• Proficiency with flow cytometry and molecular biology techniques is expected.

Responsibilities

• Carry out hands-on in vivo work in mice, including dosing and sample collection.
• Perform necropsies and support ex vivo tissue activities and readouts.
• Conduct in vitro work including multiparametric flow cytometry and molecular assays.
• Maintain accurate study records and present results to teams.
• Participate in cross-departmental meetings and discussions.
• Join dosing rotations with potential evening/weekend work.

Skills

In vivo pharmacology

Mouse handling

Flow cytometry

Molecular biology

Data analysis

GraphPad Prism

Excel

PowerPoint

Word

Education

Master’s degree + 2+ years in in-vivo work with rodents

Bachelor’s degree + 4+ years in in-vivo work with rodents

High school diploma/GED + 6 years in in-vivo work with rodents

Tools

GraphPad Prism

Excel

PowerPoint

Word

Job description

Join Amgens Mission of Serving Patients

At Amgen, if you feel like youre part of something bigger, its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do.

Since 1980, weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology, Inflammation, General Medicine, and Rare Disease we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, youll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Associate Scientist In Vivo Pharmacology, Oncology

What you will do

Lets do this. Lets change the world. In this vital role you will work onsite at Amgens South San Francisco campus as part of a fast-paced, integrated, and collaborative in vivo research team exploring therapeutics for oncology programs. You will be responsible for generating and communicating in vivo pharmacology data to support the progression of innovative oncology and immunotherapy research programs.

Key Responsibilities:

• Carry out hands-on in vivo work in mice, including handling, tumor inoculation and measurement, dosing (oral, SC, IP, and IV), blood and tissue collection, and health monitoring.
• Perform necropsies and support ex vivo tissue activities, including dissection, processing, sample preparation, and experimental readouts.
• Perform in vitro work including multiparametric flow cytometry and molecular biology techniques associated with in vivo studies.
• Strong communication to support study execution, maintain accurate study records, and present results.
• Active participation and presentation at cross-departmental teams and meetings
• Participate in dosing rotations, including occasional evening or weekend work.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The Associate Scientist we seek is a highly motivated and proactive researcher who wants to contribute to cutting edge science and serve patients with these qualifications.

Basic Qualifications:

Masters degree and 2+ years of experience in in-vivo work with rodents

OR

Bachelors degree and 4+ years of experience in in-vivo work with rodents

OR

High school diploma / GED and 6 years of experience in in-vivo work with rodents

Preferred Qualifications:

• M.S. degree in Oncology, Biology, or related disciplines, or B.S. degree with commensurate scientific / drug discovery experience and track record of scientific excellence and productivity.
• Hands-on experience with in-vivo models of cancer in an academic or industry setting and experience in pharmacology.
• Proficiency in various mouse techniques such as dosing, in vivo PK/PD/Efficacy, health monitoring, blood and tissue collection, preferably for small molecule oncology therapeutics.
• Experience with PDX models of cancer.
• Hands-on experience with in vivo bioluminescence imaging (BLI)
• Flow cytometry and multi-parametric analysis experience is strongly desired.
• Hands-on experience with molecular, cellular, and ex vivo biological techniques and assays
• Computer literacy and proficiency with GraphPad Prism, Excel, PowerPoint, Word and scientific software.
• Attention to detail, excellent organizational and communication skills, accurate & timely record keeping and data analysis.
• Pro-active, enthusiastic, show desire to learn and be part of a highly productive team.

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, well support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Application deadlineExternal/Internal postings:

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Internal only posting (or Pre-ID candidate):

Amgen anticipates accepting applications until 1 week before the posting; however, we may continue accepting applications beyond this date if we do not receive a sufficient number of candidates.

Sponsorship

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.