Associate Scientist II – Polysaccharide Conjugation

Unicon Pharma Inc; San Carlos (CA); Presencial; USD 70.000 - 100.000; Jornada completa

Descripción de la vacante

Unicon Pharma Inc. in San Carlos, California, is seeking an Associate Scientist II (Contract) to advance conjugation chemistry and analytical development for a novel polysaccharide conjugate vaccine candidate.

The role emphasizes multistep modification, purification, and thorough characterization of polysaccharides and conjugates, with DoE‑driven optimization and data‑driven decisions. The successful candidate will execute established procedures, troubleshoot with limited guidance, and

Formación

• 3–5 years of relevant laboratory experience
• Hands‑on experience with purification methods including dialysis, FPLC, and tangential flow filtration (TFF)
• Proficiency in analytical techniques such as SDS‑PAGE, Western blotting, ELISA, HPLC, SEC‑MALS
• Experience working in a regulated laboratory environment (GLP, GMP, or CLIA) is preferred
• Ability to independently execute established procedures, troubleshoot challenges, and propose next steps
• Strong attention to detail and meticulous documentation in electronic lab notebooks like Benchling

Responsabilidades

• Set up, optimize, and troubleshoot multistep polysaccharide modification and conjugation reactions.
• Purify modified polysaccharides and conjugates using dialysis, FPLC, and TFF.
• Characterize proteins, polysaccharides, and conjugates with SDS‑PAGE, Western blot, ELISA, HPLC, and SEC‑MALS.
• Apply DoE principles to design and interpret experiments for process optimization.
• Review literature to inform experimental design and troubleshooting.
• Maintain accurate records in Benchling for traceability and reproducibility.
• Present results at group meetings and contribute to development reports.
• Support lab operations, including equipment maintenance and organization.

Conocimientos

Conjugation process development

Purification methods

Analytical assays

Design of Experiments (DoE)

Data interpretation & documentation

GLP/GMP/CLIA familiarity

Educación

Bachelor's degree in chemistry/biochemistry/biology/pharmaceutical sciences

BS with 2+ years biotech/industry experience

Descripción del empleo

Unicon Pharma Inc. in San Carlos, California, is seeking an Associate Scientist II (Contract) to advance conjugation chemistry and analytical development for a novel polysaccharide conjugate vaccine candidate.

The role emphasizes multistep modification, purification, and thorough characterization of polysaccharides and conjugates, with DoE‑driven optimization and data‑driven decisions. The successful candidate will execute established procedures, troubleshoot with limited guidance, and