Associate Scientist II (Contract), Analytical Development for Characterization

Vaxcyte; San Carlos (CA); On-site; USD 70,257 - 77,145; Full time

Job summary

Vaxcyte, a leader in vaccine innovation, is seeking an Associate Scientist II in San Carlos, CA. This role requires strong expertise in mass spectrometry and analytical techniques to support vaccine characterization.

The ideal candidate should possess a BS in Chemistry or related field, with at least 2 years of industry experience, and a solid understanding of analytical workflows. The position offers a contract length of 12 months with hourly compensation ranging from $51 to $56.

Qualifications

• Minimum 2 years of relevant industry experience.
• Hands-on experience with mass spectrometry platforms.
• Excellent organizational skills and attention to detail.

Responsibilities

• Prepare samples and perform analyses per SOPs.
• Execute analytical assignments with accuracy and efficiency.
• Conduct rigorous data analysis and present findings.

Skills

Mass spectrometry platforms

LC-MS workflows

Data analysis

Cross-functional collaboration

Education

BS in Chemistry or related discipline

MS in Chemistry or related discipline (without experience)

Tools

Orbitrap mass spectrometers

qTOF mass spectrometers

Triple quadrupole mass spectrometers

Job description

Join our Mission to Protect Humankind!

Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked. Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, and Shigella is just the beginning. Our path to success is clear and well-defined, and Vaxcyte is set up to go the distance.

Summary:

We are seeking a highly skilled and motivated Associate Scientist II (Contract) to join our Analytical Development team to support the characterization of drug substances, protein intermediates, and drug products using LC-MS and complementary analytical techniques. The ideal candidate would be central to implementing mass spectrometry-based workflows, interpreting complex data, and collaborating cross-functionally to advance our vaccine programs.

Essential Functions:

• Prepare samples and perform analyses per SOPs, including detailed data interpretation.
• Independently execute analytical assignments with accuracy and efficiency.
• Implement LC-MS workflows for proteins, conjugates, and other in-process molecules.
• Operate, maintain, and troubleshoot Orbitrap, qTOF, and triple quadrupole mass spectrometers.
• Conduct rigorous data analysis, interpret results, and present findings in team meetings.
• Partner cross-functionally to develop analytical strategies and support their needs.
• Maintain accurate documentation in an electronic lab notebook system.

Requirements:

• BS in Chemistry, Analytical Chemistry, Biochemistry, or a related discipline, with minimum 2 years of relevant industry experience. MS without experience; or equivalent work experience.
• Hands‑on experience utilizing mass spectrometry platforms, including hybrid Orbitraps, qTOFs, and triple quadrupoles.
• Familiar with peptide mapping, and intact protein analysis workflows.
• Excellent organizational skills, attention to detail, and documentation expertise.
• Strong scientific curiosity and problem‑solving abilities.
• Effective communication and collaboration within cross‑functional environments.
• Ability to rapidly learn analytical workflows and technologies.
• Experience using electronic lab notebook (ELN) systems is a plus.
• Scientific creativity and curiosity for applying new technologies to complex analytical challenges.

Reports to: Scientist II, Analytical Development

Location: San Carlos, CA

Expected Contract Length: 12 months

Hourly Range: $51/hr. - $56/hr.

We are an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status.