Associate Scientist II - Biologics Drug Product Development

AbbVie; San Francisco (CA); On-site; USD 59,000 - 111,000; Full time

Job summary

AbbVie Inc. in South San Francisco, CA, is seeking an Associate Scientist II for on-site work in the Biologics Drug Product Development group. The role focuses on stability studies, analytical characterization, data analysis, and reporting to support clinical development programs.

The position requires a strong background in protein chemistry, analytical methods, and collaboration within matrixed teams. Lab-based, full-time opportunity with competitive compensation and growth potential.

Qualifications

• Bachelor’s degree required in chemistry or related field.
• 3-5 years of experience with biology/biochem or related role preferred.
• Experience with protein characterization and stability testing.
• Strong verbal and written communication skills.

Responsibilities

• Own & support stability/in-use/process studies for development drug product batches.
• Perform analytical assays to evaluate protein and excipients stability.
• Analyze results and communicate updates to the team; document in ELN.
• Write technical reports to support regulatory filings and study findings.
• Collaborate with matrixed teams to support pipeline programs.

Skills

Protein chemistry

Analytical troubleshooting

Cross-functional collaboration

Documentation & ELN

Education

Bachelor’s degree in chemistry, chemical engineering, biochemistry, pharmaceutical sciences or equivalent

Master’s degree with 0-2 years experience

Tools

SEC

CEX

iCIEF

CE‑SDS

HIAC

MFI

Job description

Associate Scientist II - Biologics Drug Product Development

• Full-time
• Salary Min: 58656
• Salary Max: 110500
• Workday Global Grade: 13
• Compensation: USD 58,656 - USD 110,500 - yearly

About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com . Follow @abbvie on LinkedIn, Facebook , Instagram , X and YouTube.

The Biologics Drug Product Development group within AbbVie is a global organization responsible for developing and characterizing drug product formulations and manufacturing processes for biologic therapeutics (antibodies, antibody-drug conjugates (ADCs), neurotoxins, and novel biologic formats) from preclinical development through clinical proof of concept.

We have an exciting opportunity available for an Associate Scientist II to join our team at our Bay Area site in South San Francisco, CA. This is a lab-based position and requires fulltime on-site presence. Successful candidates will thrive in a collaborative lab environment.

Key responsibilities include:

• Own & support stability / in-use / process studies: work within the process operations team to fill development drug product batches for GLP toxicology studies, reference standard fills, and representative drug product batches. Develop skills to plan and execute screening, in-use, and formulation stability studies to support formulation and process development for clinical trials.
• Perform analytical assays & support troubleshooting: conduct analytical assays to evaluate protein and excipients stability (i.e. HPLC/UPLC, SEC, CEX, CE‑SDS,icIEF, UV-Vis, CD, Karl Fischer titration, HIAC, MFI). Generate high-quality data to support selection of formulation composition, development of dose administration guidance, and drug product manufacturing instructions. Develop the skills to independently troubleshoot assays and instruments to ensure consistent quality data output.
• Analyze & communicate results: analyze study results, organize and document the results in an electronic lab notebook (ELN), and effectively communicate updates, troubleshooting, and results to the team. Interpret results and draw conclusions from multistage experiments with support from study owners and project leads. Communicate aberrant data and lab issues to management to gain input and alignment on solution.
• Write technical reports and communicate technical updates: Author technical reports to support regulatory filings and present the study results and findings to the team
• Collaboration: Collaborate closely with highly matrixed team members to support pipeline programs and participate in project teams as a study owner

**Equal Opportunity Employer Minorities/Women/Veterans/Disabled**

• Degree in chemistry, chemical engineering, biochemistry, pharmaceutical sciences or equivalent
  • Bachelor’s degree and typically 3-5 years of experience or master’s degree and typically 0-2 years of experience.
• Strong technical background encompassing protein chemistry and protein handling.
• Hands-on experience with running and troubleshooting analytical techniques used for protein characterization and stability testing such as SEC, CEX, iCIEF, CE-SDS, HIAC, and MFI.
• Ability to work in cross-matrixed team supporting multiple projects and participate in project-focused teams.
• Technical ability to execute and troubleshoot experiments through rational and critical thinking. Must be highly organized and detail oriented.
• Eagerness to learn and apply new scientific techniques.
• Excellent verbal and written communication skills.
• Strong collaborative skills for working effectively within the team.
• Prior experience in protein formulation development, process development, drug delivery, or analytical functions is highly preferred.
• Prior experience utilizing automated liquid handlers and/or executing high-throughput screening workflows is highly preferred.

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law:

• The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at thetimeofthis posting based on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographiclocation,andwemayultimatelypaymore or less than the posted range. This range may bemodifiedin thefuture.
• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees.
• This job is eligible toparticipatein our short-term incentiveprograms.

Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.Theamountandavailabilityof anybonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employeeremainsin the Company'ssoleandabsolutediscretion unless and until paid andmay bemodifiedat the Company’s sole and absolute discretion, consistent withapplicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.