Associate I, PDT

Replimune; Framingham (MA); On-site; USD 72,000 - 93,000; Full time

Benefits offered by this job

Medical Insurance

Dental Insurance

Vision Insurance

401k match

Paid holidays

Job summary

Replimune seeks an Associate I, PDT in Framingham to support day-to-day PDT laboratory operations. You will perform routine upstream/downstream processes and drug product formulation tasks, under supervision, with a focus on documentation and GMP-compliant practices. The role requires a Bachelor’s degree and 0–2 years in a biotech lab.

The position is based on-site in Framingham, with a typical 5-day on-site expectation and a base pay range of $72,000–$93,000, plus incentives and benefits.

Qualifications

• Hands-on laboratory experience required in a biotech/pharma setting.
• Experience with cell culture, purification or formulation is a plus.
• Ability to follow SOPs and record data accurately.
• Self-motivated, organized, able to multitask and work in a small team.

Responsibilities

• Support upstream tissue culture, downstream virus purification and drug product formulation activities.
• Perform routine lab and pilot-scale steps with supervision, including setup, sampling, cleaning and documentation.
• Maintain stock levels and prepare reagents following proper documentation practices.
• Ensure GMP compliance and proper lab housekeeping and safety.

Skills

Lab techniques

Cell culture

Purification/Chromatography

Documentation

Time management

Communication

Teamwork

Education

Bachelor's degree

Job description

Overview

Replimune's mission is to revolutionize cancer treatment with therapies designed to activate a powerful and durable full-body anti-tumor response, boldly transforming cancer care because patient's lives depend on it.

At Replimune, we live by our values:

United: We Collaborate for a Common Goal.

Audacious: We Are Bold.

Dedicated: We Give Our Full Commitment.

Candid: We Are Honest With Each Other.

People are at the center of everything we do, and when it comes to our employees, we make it personal. With a deep sense of purpose, a strong and evolving culture, a competitive and forward-looking total rewards program, everyone at Replimune has a unique opportunity to impact on the lives of patients, caregivers and themselves.

Join us, as we reshape the future.

Summary of job description:

The Associate I, PDT is responsible for supporting the day-to-day operation of the PDT laboratories and process activities. The Associate I will perform routine upstream, downstream and drug product formulation process steps to support projects and will provide support for process characterization and formulation development activities.

This position is based in our Framingham location and typically has a 5-day on-site expectation.

Key responsibilities:

• Support upstream tissue culture, downstream virus purification and drug product formulation activities within the PDT laboratory.
• Perform routine laboratory and pilot lab process steps under supervision, including preparation, equipment set-up, sampling, cleaning and documentation.
• Perform general laboratory housekeeping tasks, including maintaining stock levels of laboratory consumables and preparation of reagents while executing good documentation practices.
• Support general laboratory upkeep, including ensuring the laboratory is clean, disposal of waste, sample storage and equipment monitoring.
• When required, operate in accordance with Good Manufacturing Practice (GMP) and company procedures.
• Work in cross-functional teams with Manufacturing, Quality Control, Facilities and Engineering, Analytical Development and Quality Assurance.
• Ensure effective, high-quality, timely and appropriate documentation in laboratory notebooks.

Other responsibilities:

• Participate with other members of the PDT team in the preparation and purification of viruses, thereby gaining both theoretical and practical knowledge of upstream and downstream processes.
• Support review of batch records, laboratory notebooks and GMP documentation as appropriate.
• Provide support to the facilities group when required.
• Practice and promote safe working habits and adhere to safety procedures and guidelines.

Educational requirements:

• Bachelor's degree with 0-2 year of related work experience.

Experience and skill requirement:

Hands-on experience in a laboratory setting is desired. Experience in the biotech or pharmaceutical industry is desired. Experience in cell culture, purification, chromatography or formulation would be beneficial. The successful candidate will have the ability to follow protocols and standard operating procedures and the ability to record data in a timely and accurate manner in accordance with procedures. The candidate should be self-motivated, organized, able to manage time effectively, communicate well, work independently and as part of a small team, and work flexibly to meet varying workloads.

Salary Range

Replimune is committed to fair and equitable compensation practices, and we strive to provide employees with total compensation packages that are market competitive. For this role, the anticipated base pay range is $72,000 -$93,000.The exact base pay offered for this role will depend on various factors, including but not limited to the selected candidate's unique set of qualifications, skills, and experience. Our current organizational needs also play a part in determining your final offer.

At Replimune, base pay is only one part of your total compensation package. The selected candidate will be eligible for an annual performance incentive bonus, new hire equity, and ongoing performance-based equity. Replimune also offers various benefits offerings, including, but not limited to, medical, dental, and vision insurance, 401k match, flexible time off, and a number of paid holidays including year-end shutdown.

About Replimune

Replimune Group, Inc., headquartered in Woburn, MA, founded in 2015 with the mission to transform cancer treatment by pioneering the development of a novel portfolio of oncolytic immunotherapies. Replimune's proprietary RPx platform is based on a potent HSV-1 backbone intended to maximize immunogenic cell death and the induction of a systemic anti-tumor immune response. The RPx platform is designed to have a unique dual local and systemic activity consisting of direct selective virus-mediated killing of the tumor resulting in the release of tumor derived antigens and altering of the tumor microenvironment to ignite a strong and durable systemic response. The RPx product candidates are expected to be synergistic with most established and experimental cancer treatment modalities, leading to the versatility to be developed alone or combined with a variety of other treatment options. For more information, please visit www.replimune.com.

We are an Equal Opportunity Employer.