Associate Director, Quantitative Pharmacology

Regeneron Pharmaceuticals; Village of Tarrytown (NY); On-site; USD 176,000 - 287,000; Full time

Benefits offered by this job

Annual bonus

Equity awards

Pension plan

401(k)

Health & wellness programs

Fitness centers

Insurance (medical, dental, vision, 
L

Paid time off

Family support benefits

Job summary

Regeneron Pharmaceuticals in Tarrytown, NY, seeks an Associate Director to lead model-informed drug development within the Quantitative Pharmacology group. The role focuses on PK/PD modeling, exposure–response analyses, and regulatory support across modalities including antibodies, siRNA, and gene therapies.

The AD will guide cross‑functional teams, mentor scientists, and drive innovations in quantitative tools while ensuring regulatory compliance and high-quality deliverables.

Qualifications

• PhD in Quantitative Pharmacology or related field required.
• 6+ years post‑doc or industry experience; MS with 9+ years acceptable.
• Proven expertise in population PK/PD, exposure–response, or mechanistic modeling (QSP).

Responsibilities

• Lead model-informed development strategies to support regulatory and clinical decisions.
• Deliver population PK/PD, exposure–response, and translational modeling analyses.
• Represent QP in program and governance meetings and communicate insights clearly to non‑modeling audiences.
• Contribute to regulatory interactions and author key regulatory documents related to QP (IB, briefing books).
• Mentor and develop junior scientists and foster scientific rigor and collaboration.
• Identify and implement advanced modeling approaches and quantitative tools for efficiency and impact.
• Ensure analyses and documentation meet high scientific quality and regulatory compliance.

Skills

Population PK/PD

Exposure–Response

Regulatory submissions

Communicating results

Education

PhD in Quantitative Pharmacology/Pharmacometrics/Engineering or related field

MS with 9+ years of relevant experience

Tools

NONMEM

Monolix

Simulx

MATLAB/Simbiology

R

Job description

Build our future together:

We are seeking a highly motivated Associate Director (AD) to join the Quantitative Pharmacology (QP) group. The AD will lead model-informed drug development strategies supporting one or more therapeutic areas across modalities including antibodies, siRNA, and gene therapies. This role combines scientific depth with cross-functional leadership to inform dose selection, trial design, and regulatory strategy from early development through submission.

When & where:

• Location: Tarrytown, NY, Cambridge, MA, Warren, NJ, Remote, USA

• Work model/flexibility: 4 days onsite

Discover your role:

• Driving model-informed development (MIDD) and pharmacometrics strategies in partnership with Clinical Pharmacology, Biostatistics, Clinical and Translational teams to support regulatory and clinical decision-making.

• Leading the QP evaluation of one or more assets, accountable for timely delivery of population PK/PD, exposure–response, and translational modeling analyses.

• Representing QP at program and governance meetings, communicating quantitative insights clearly to non-modeling audiences.

• Contributing to regulatory interactions and authoring key components of regulatory documents related to QP (e.g., IB, briefing books, etc.).

• Mentoring and developing junior scientists and fostering a culture of scientific rigor and collaboration.

• Identifying and implementing process improvements, new modeling approaches, and innovative quantitative tools to enhance efficiency and impact.

• Ensuring analyses and documentation are of the highest scientific quality and regulatory compliance.

This role requires:

• PhD in Quantitative Pharmacology, Pharmacometrics, Engineering, or a related field

• 6+ years of post-doctoral or industry experience; or MS with 9+ years of relevant experience.

• Demonstrated expertise in population PK/PD, exposure–response, or mechanistic modeling (systems biology, or QSP) using tools such as NONMEM, Monolix, Simulx, MATLAB/Simbiology and R.

• Proven track record of delivering analyses supporting regulatory submissions and engaging directly with agencies (e.g., FDA, EMA, PMDA).

• Hands‑on experience with a broad range of quantitative and computational tools and a strong publication record.

• Exceptional communication and interpersonal skills, with the ability to influence and partner effectively across technical and non‑technical teams.

Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits. Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role:

• annual bonuses or other incentive plans
• equity awards
• pension or retirement benefits
• 401(k) company match
• health and wellness programs
• fitness centers
• insurance benefits (e.g. medical, dental, vision, life and disability)
• paid time off
• family support benefits

For additional information about Regeneron benefits in the U.S., please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other locations, additional information will be provided during the recruitment process. If you have any questions, please speak with your recruiter.

Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed on‑site. Please speak with your recruiter and hiring manager for more information about on‑site expectations for your role and location.

As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.

For jobs in Canada: this posting is for an existing position.

We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Salary Range (annually)

$176,100.00 - $287,300.00