Associate Director, Portfolio Management

Revolution Medicines, Inc.; San Francisco (CA); On-site; USD 186,000 - 233,000; Full time

Job summary

Revolution Medicines, Inc. is seeking a senior professional to lead Portfolio Management and cross-functional analytics for our oncology programs at our Redwood City headquarters.

You will partner with PDM leadership to plan, budget, and drive strategic decision-making across the organization. The role requires 8+ years in CMC, PPM, or life sciences consulting, strong analytical and communication skills, and the ability to influence across functions in a fast-paced environment.

Qualifications

• 8+ years in CMC, portfolio management, or life sciences consulting.
• Strong analytical and problem-solving with scenario planning, forecasting, and business analytics.
• Ability to influence across functions and communicate with senior leadership.
• Proven track record in fast-paced, ambiguous environments.

Responsibilities

• Partner with PDM leadership and stakeholders for portfolio planning and strategic decisions.
• Lead analyses, insights, and recommendations for prioritization and resource allocation.
• Develop portfolio reports, dashboards, and decision-support tools for visibility into performance, risks, and opportunities.
• Drive cross-functional governance and planning to ensure alignment and follow-through on actions.
• Support budgeting and long-range planning with data analysis and scenario modeling.
• Communicate findings and recommendations clearly to senior leadership.

Skills

Analytical thinking

Problem solving

Communication skills

Stakeholder management

Project management

Cross-functional collaboration

Executive storytelling

Education

Bachelor of Science or equivalent

Advanced degree (preferred)

Tools

PMP Certification

Job description

Revolution Medicines is a global, commercial-state oncology company dedicated to discovering, developing and delivering innovative medicines for patients with RAS-addicted cancers. Leveraging its differentiated RAS(ON) tri-complex inhibitor platform, the company is advancing a broad, integrated portfolio of oral RAS(ON) inhibitors designed to directly target the active, cancer-driving state of RAS. Founded on rigorous scientific inquiry and a willingness to challenge long-held assumptions, Revolution Medicines is committed to changing the trajectory of disease for patients with RAS-addicted cancers worldwide.

Our people are united by a shared way of working: follow the science, challenge assumptions, act with urgency and hold ourselves to a high standard of rigor - all in service of patients.

The Opportunity:

• Partner with PDM leadership and cross-functional stakeholders to support portfolio planning, business operations, and strategic decision-making across the organization.
• Lead development analyses, insights, and recommendations that enable effective prioritization, resource allocation, risk management, and execution of business objectives.
• Lead portfolio reporting, metrics, dashboards, and other decision-support tools to provide visibility into portfolio performance, organizational capacity, risks, and opportunities.
• Lead or contribute to strategic initiatives and operational excellence efforts aimed at improving business processes, organizational effectiveness, and scalability.
• Drive cross-functional planning and governance activities by facilitating stakeholder alignment, supporting decision-making forums, and ensuring effective follow-through on key actions and commitments.
• Support budgeting and long-range planning activities by driving data analysis, scenario modeling, and business insight generation.
• Apply structured problem-solving and analytical approaches to address complex cross-functional challenges and support informed decision-making.
• Build strong partnerships across PDM and adjacent functions to promote transparency, alignment, and effective execution of key priorities.
• Prepare and deliver clear, concise, and compelling communications, presentations, and recommendations for audiences ranging from working teams to senior leadership.

Required Skills, Experience and Education:

• B.Sc. in a scientific, engineering, business, or related discipline, with 8+ years of experience within a CMC, Project and Portfolio Management, and/or life sciences management consulting organization.
• Robust analytical and problem-solving skills with experience in scenario planning, forecasting, resource modeling, and business analytics; demonstrated ability to translate analytical insights into executive-level communications.
• Strong scientific and business acumen with the ability to connect data, portfolio priorities, resource constraints, and organizational objectives into actionable recommendations.
• Demonstrated intellectual curiosity and learning agility, with a willingness to quickly develop expertise in new business processes, functional areas, and technical domains.
• Ability to influence without authority and build productive working relationships across functions and organizational levels.
• Exceptional communication and storytelling skills with the ability to synthesize complex information into clear, concise, and compelling recommendations for senior leadership.
• Demonstrated ability to balance strategic thinking with operational execution and deliver results across complex cross-functional initiatives.
• Demonstrated success operating in fast-paced, dynamic environments with evolving priorities and ambiguity.
• Proven track record of taking ownership, identifying opportunities for improvement, and proactively driving solutions with minimal direction.
• Strong project management and facilitation skills with the ability to drive alignment, manage competing priorities, and execute effectively in ambiguous environments.

Preferred Skills:

• Advanced degree in a scientific, engineering, business, or related discipline.
• PMP or similar project management certification.

The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.

Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.

Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.

Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCAA Notice and Privacy Policy. For additional information, please contact [e-mail].

Base Pay Salary Range

$186,000 - $233,000 USD