Associate Director, Data Science - Functional Genomics & AI

EyeBio; United States; Hybrid; USD 176,000 - 277,000; Full time

Benefits offered by this job

Hybrid work arrangement

Job summary

Merck in Cambridge, MA seeks an Associate Director of Data Science to lead Functional Genomics analytics, directing hit calling, multi-evidence integration, and ML-driven decision support across discovery programs.

You will mentor a team of scientists, shape early discovery directions, and collaborate with cross-disciplinary teams to build scalable analytics for CRISPR screens and multi-omics integration. A PhD is preferred.

Qualifications

• MS in computational biology, bioinformatics, biostatistics, biophysics, mathematics, statistics, genetics/genomics, computer science or related STEM and 8+ years of experience.
• Passion for solving biological problems with computational methods and strong execution.
• Experience with computational analysis, algorithm development, and interpretation of large-scale NGS/functional genomics data.
• Proven track record applying ML to analyze single-cell RNA-seq data for insights.

Responsibilities

• Lead design and build scalable analytics frameworks for pooled, arrayed, single cell, and optical CRISPR screens.
• Invent scalable methods for functional genomics and multi-evidence target prioritization.
• Build image analysis pipelines for high content/optical screens and convert phenotypes to insights.
• Integrate genomics, imaging, transcriptomics, and proteomics data for target prioritization.
• Apply AI/ML including LLM-powered workflows to triage targets and synthesize evidence.
• Mentor scientists, set technical direction, and promote reproducible research and FAIR data practices.
• Collaborate with experimentalists, software engineers, and external partners to advance platforms.

Skills

R

Python

Git

AWS

Linux

NGS data analysis

Single-cell RNA-seq

Machine learning

Image analysis

Education

MS in computational biology or related STEM

PhD in related field (preferred)

Tools

R Shiny

Git

AWS

Linux

Job description

Merck in Cambridge, MA seeks an Associate Director of Data Science to lead Functional Genomics analytics, directing hit calling, multi-evidence integration, and ML-driven decision support across discovery programs.

You will mentor a team of scientists, shape early discovery directions, and collaborate with cross-disciplinary teams to build scalable analytics for CRISPR screens and multi-omics integration. A PhD is preferred.